Research Associate - San Diego, CA | Biospace
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Research Associate

R&D Partners

San Diego, CA
Posted Date:
Position Type:
Job Code:
Required Education:
Bachelors Degree
Areas of Expertise Desired:
Antibody, Elisa,

Job Description

Primarily be responsible for developing and performing binding assays, kinetic profiling assays, competition assays, efficacy assays and epitope binning of early therapeutic candidates using a wide range of biophysical and biochemical methods including Biacore, MASS-1, Octet, FRET, ELISA, etc. 
Implement and validate protocols. 
Reviewing literature for technical support. 
Data analysis. 
With assistance, executes experiments, conducts analysis and reports results. 
Work with minimal direction to complete assigned tasks. 


At least 2 years of industry experience in bioanalytical and biophysical characterization of monoclonal antibodies, Fc-fusion proteins, peptides and antibody-drug conjugates (ADCs). 
***MUST have experience with Bicaore or SPR instruments.*** 
Proven track record of developing binding assays for monoclonal antibodies and other forms of biologics candidates using all or any of the following techniques: Biacore, MASS-1, Octet, HTRF, AlphaScreen, ELISA. 
Thermal stability determination using DSC, DSF and formulation screen to identify ideal storage buffer condition. 
Experience in SDS PAGE is a plus. 
Antibody conjugation experience is a plus. 
Experience in protein expression and purification is a plus. 
Mass spectrometry: Intact mass determination of antibodies and Fc-fusion protein can be an added advantage. 

Bachelor’s or Master’s degree in Biochemistry or related discipline with 2 years of hands on experience in industry focusing on Biologics. NO PHDs.

Candidates local to San Diego