Senior Research Associate, Antibody/ADC Analysis & Purification - Emeryville, CA | Biospace
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Senior Research Associate, Antibody/ADC Analysis & Purification

Catalent Pharma Solutions, Inc.

Emeryville, CA
Posted Date:
Position Type:
Full time
Job Code:
Required Education:
Bachelors Degree
Areas of Expertise Desired:
Antibody, Biology, Biotechnology, Chemistry, HPLC, Pharmaceutical,

Job Description

Catalent Biologics-West (formerly Redwood Bioscience) has developed a protein-chemical engineering technology to produce the next-generation of antibody- drug conjugates (“ADCs”) and other semi-synthetic biotherapeutics. The Company’s proprietary SMARTagTM site-specific protein modification technology, novel conjugation chemistry and proprietary cytotoxin-linkers enable the generation of homogenous bioconjugates engineered to enhance potency, safety and stability. The technology employs natural post-translational modifications found in human cells to site-specifically create one or more aldehyde tags on protein molecules. These chemical handles are then stably conjugated to cytotoxic payloads to prevent their systemic release. The SMARTagTM platform provides precise payload positioning and defined stoichiometry of payload–protein ratios. The control afforded by the technology also enables identification of superior drugs from libraries of differentially designed conjugates. Our Emeryville, CA site is hiring for multiple positions, visit us online and apply today!

Catalent is seeking a Senior Research Associate who will be responsible for the development and execution of cell and antibody based assays. In addition, this position will focus on the purification and analysis of antibody drug conjugates (ADCs).

The Role (daily responsibilities)

* Performs and optimizes existing analytical assays, including ELISA, flow cytometry, in vitro cytotoxicity, and HPLC based methods.
* Develops methods for new analytical assays.
* Maintains mammalian cell cultures.
* Performs FPLC/AKTA based protein purifications.
* Functions as a key contributing member of the chemical biology team and communicates results across in-house teams.
* Generates data to support strategic partner relationships, platform development, patents, and publications.
* Performs DOE, carries out experiments, and compiles and analyzes data.
* Works on projects involving research/innovation and process improvements.
* Works on special client projects, including client interaction as appropriate/necessary.
* Identifies and makes preliminary independent decisions on experimental and client work.
* Writes complex procedural SOPs, batch production records, and drafts reports.
•Accurately reviews batch records and other data, ensuring consistency.
* Accurately ships purified samples to clients and fills out appropriate paperwork.
•Executes small and pilot scale experiments independently.
* Maintains documentation of experiments and/or batch records according to good documentation practices.
* Troubleshoots and problem solves to initiate and execute/monitor corrective actions.
* Performs general lab housekeeping tasks.
* Accurately completes routine and preventative maintenance on laboratory equipment.
* Actively participates in team meetings.


The Candidate (requirements)

* BS or MS degree in cell biology, biochemistry, or a related scientific discipline with up to 15 years of experience in pharma or biotech industry.
* Significant cell culture experience in the biopharmaceutical industry is highly desired.
* Knowledge with AKTA based protein purification and HPLC based protein analysis.

Position Benefits

* Potential for career growth within an expanding team
* Defined career path and annual performance review and feedback process
* Medical, Dental, Vision and 401K are all offered from Day One of employment
* 19 days of paid time off annually + 7 paid holidays

About Catalent

Catalent offers rewarding opportunities to further your career!  Join the global drug development and delivery leader and help develop some of the nearly 200 products we launch each year or help supply over 7,000 products for patients around the world. Catalent is an exciting and growing international company where our professionals work directly with pharma, biopharma and consumer health companies of all sizes to advance new medicines from early development to clinical trials and to the market, for the benefit of patients globally.

Catalent. More products. Better treatments. Reliably supplied.™

Visit to explore career opportunities, or contact us at +1 877 503 9493.

Catalent is an Equal Opportunity / Affirmative Action employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability, or protected veteran status. If you require reasonable accommodation for any part of the application or hiring process due to a disability, you may submit your request by sending an email along with the job number and title to This option is reserved for individuals who require accommodation due to a disability. Information received will be routed to a recruiter who will provide assistance to ensure appropriate consideration in the application or hiring process.

Notice to Agency and Search Firm Representatives: Catalent Pharma Solutions (Catalent) is not accepting unsolicited resumes from agencies and/or search firms for this job posting.  Resumes submitted to any Catalent employee by a third party agency and/or search firm without a valid written & signed search agreement, will become the sole property of Catalent.  No fee will be paid if a candidate is hired for this position as a result of an unsolicited agency or search firm referral.  Thank you.