Senior Research Associate - South San Francisco, CA | Biospace
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Senior Research Associate

CytomX Therapeutics, Inc.

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Location:
South San Francisco, CA
Posted Date:
5/17/2017
Position Type:
Full time
Job Code:
Salary:
Required Education:
Bachelors Degree
Areas of Expertise Desired:
Oncology, Senior Research Associate,

Job Description


CytomX Therapeutics is unlocking the potential of antibody therapeutics in oncology by developing a novel therapeutic antibody class of highly targeted Probody™ therapeutics. The current opening offers an opportunity to participate in moving novel Probody Therapeutics toward clinical investigation in a fast-moving and dynamic R&D environment.

We seek a highly motivated and team oriented individual to develop and characterize Probody Therapeutics to novel targets for the treatment of cancer. The successful candidate will work as a bench Senior Research Associate in the Oncology Department and will participate in the evaluation of oncology targets, design and optimization of Probody Therapeutics, and the development of preclinical assays to support the development of drug candidates.  

Responsibilities
•   Screening and construction of combinatorial libraries for the discovery of Probody Therapeutics
•   Design, construction, and expression of novel Probody Therapeutics.  
•   Perform biochemical, molecular, and functional assays to characterize Probody Therapeutics i.e. ELISA, Octet, and cell based binding and functional assays.
•   Follow established protocols, as well as develop and apply new protocols as needed.
•   Independently design, implement and analyze experiments, as well as follow and incorporate relevant published findings related to research, methodologies and technologies
•   Troubleshoot assay performance and sample testing as needed
•   Utilize literature to increase knowledge base and implement improvements
•   Interpret and analyze data, helping to incorporate results into overall scientific projects
•   Prepare and present technical information at internal/external meetings and contribute technical information for group presentations
•   Maintain vendor relationships, service contracts, and interact with CRO’s
•   Keep accurate and up-to-date records, communicate results and propose scientifically based recommendations

Requirements


•   BS/MS in biochemistry, molecular biology, or a related field, with a minimum of six years’ industry experience preferred
•   A background with protein engineering is strongly preferred
•   Motivated self-starter who can work independently and collaboratively in a dynamic team environment with a conscientious attitude and enthusiasm
•   Demonstrated experience with the design, cloning, and expression of proteins
•   Experience with the screening and construction of combinatorial libraries
•   Experience with flow cytometry is a plus
•   Strong analytical and critical thinking skills with the ability to interpret complex data
•   Excellent written and verbal communication skills
•   Ability to work in a fast-paced environment and the flexibility to align daily work with project needs are crucial

CytomX is an equal opportunity employer. Employment decisions are based on merit and business needs. CytomX will not discriminate against any job applicant because of race, color, national origin, ancestry, gender, sexual orientation, age, religion, creed, physical or mental disability, gender identity, medical condition, pregnancy, marital status, veteran status, or any other characteristic protected by federal, state or local law.