Senior Associate Scientist Immuno Assay - San Francisco, CA | Biospace
Get Our FREE Industry eNewsletter

Senior Associate Scientist Immuno Assay

Amgen

Apply
Location:
San Francisco, CA
Posted Date:
12/2/2016
Position Type:
Full time
Job Code:
R-29193
Salary:
Required Education:
Bachelors Degree
Areas of Expertise Desired:

Job Description

The department of PKDM within Amgen is dedicated to the discovery and development of safe and effective medicines by elucidating the absorption, distribution, metabolism, excretion and pharmacokinetic properties of novel therapeutic drug candidates to improve their pharmacological potential. PKDM works in close partnership with disciplines such as protein science, pharmacology, toxicology, pharmaceutical sciences, clinical pharmacology and regulatory to engineer promising clinical therapeutic candidates, conduct preclinical development studies, support clinical evaluation and contribute to IND and NDA filings.

Responsibilities:

Develop and routinely employ bioanalytical methods for the quantitative and qualitative analysis of new protein/mAb entities in plasma, tissues, and other biological matrices, as well as, interpret and provide bioanalytical results to project team representatives in support of drug discovery and development.  

Independently design and execute experiments to quantitate molecular entities by immunoassay (ELISA, Gyros, MSD) in support of both drug discovery and early development programs.

Understand preclinical ADME and bioanalytical techniques

Work as a member of the bioanalytical group and will be responsible for sample preparation, tissue homogenization, affinity capture, data generation and analysis with Watson-LIMS

Assist in troubleshooting when instrument or assay problems arise

Basic bioanalytical research, electronic laboratory notebook keeping and communication of results to project teams.

Requirements

Basic Qualifications:

Master's degree & 3 years of scientific experience
OR
Bachelor's degree & 5 years of scientific experience

Preferred Qualifications:

BS or MS in biology, chemistry, biochemistry, immunology or equivalent Experience with independent operation of various automated immunoassay platforms

Excellent oral and written communication skills

Work collaboratively in a fast-paced work environment