Senior Associate Scientist - Conjugation & Polytides - Chesterfield, MO | Biospace
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Senior Associate Scientist - Conjugation & Polytides

Pfizer Inc.

Chesterfield, MO
Posted Date:
Position Type:
Full time
Job Code:
Required Education:
Bachelors Degree
Areas of Expertise Desired:

Job Description

A career at Pfizer offers opportunity, ownership and impact.

All over the world, Pfizer colleagues work together to positively impact health for everyone, everywhere. Our colleagues have the opportunity to grow and develop a career that offers both individual and company success; be part of an ownership culture that values diversity and where all colleagues are energized and engaged; and the ability to impact the health and lives of millions of people. Pfizer, a global leader in the biopharmaceutical industry, is continuously seeking top talent who are inspired by our purpose to innovate to bring therapies to patients that significantly improve their lives.


The Senior Associate Scientist position within the Conjugation and Polytides Process Development (CPPD) group is laboratory based position for performing chemistry, biochemistry and bio-conjugation process development of bio therapeutic products from pre-clinical and Ph I / 2 clinical trials through commercialization. The position will involve use of innovative and modern techniques to develop and characterize processes for candidate molecules to meet project needs. The incumbent will assist in the development and scale-up of processes from bench top to pilot-scale and, as required, technology transfer to commercial plants. The Associate Scientist must be able to interact effectively with a multi-disciplinary team of scientists for formulation optimization and overall candidate progression. Effective communication skills are required for interactions with laboratory scientists, project managers and colleagues from numerous functions serving on multi-disciplinary project teams.

ROLE RESPONSIBILITIESWorking within a team environment:

  • Develops scalable, robust, efficient, and innovative chemical and biochemical conjugate processes suitable for clinical material production and commercialization.
  • Supports transfers to pilot and commercial facilities for the production of clinical and commercial materials.
  • Supports necessary purification activities to produce drug substances with appropriate quality attributes.
  • Contributes to the preparation of technical reports and regulatory filings, makes oral presentations to engineers, scientists and management, and contributes to external publications.
  • Performs all duties associated with the operation of effective research laboratories.



  • BS with 2-5 years' experience or M.S. with 0-2 years in Organic Chemistry, Biochemistry, Biochemical Engineering, Chemical Engineering or equivalent.
  • Knowledge of drug development processes for progression of biological candidates.
  • Familiarity with GLP/GMP requirements. Familiarity in scale-up and technology transfer to pilot/commercial scale.
  • Excellent oral and written communication skills. The successful candidate will possess strong oral and written communication skills. Strong analytical and computer skills are required.

  • Knowledge of synthetic chemistry route optimization
  • Knowledge of peptide and/or oligonucleotide chemistry and synthesis
  • Knowledge of bio-conjugation and characterization
  • Experience with protein analytical methods (e.g. SE-HPLC, SDS-PAGE, Capillary Electrophoresis, IEF, etc.)
  • Familiarity with parenteral manufacturing requirements, including filtration, container/closure

EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.

Sunshine Act

Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.

Additional Offer Details:

  • Last Date to Apply for Job: September 27, 2017
  • This job is Pfizer Exempt US Grade: 4
  • Eligible for Employee Referral Bonus