Scientist/Sr. Scientist - Hayward, CA | Biospace
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Scientist/Sr. Scientist

PACT Pharma, Inc.

Hayward, CA
Posted Date:
Position Type:
Full time
Job Code:
Required Education:
Areas of Expertise Desired:
Biotechnology, Cancer, Cell, Cytometry, Drug Discovery, Engineering, Flow Cytometry, Laboratory, Oncology, PhD, Protein Chemistry, Research Scientist, Scientist, Scientist Oncology, Vivo,

Job Description

We are currently recruiting a highly qualified Scientist/Sr. Scientist for protein engineering to facilitate isolation and testing of these engineered neo-epitope targeted TCR-T cells. We are located in the San Francisco bay area, in the heart of the world’s premier biotechnology research hub. PACT Pharma offers a competitive compensation and benefits package, including aggressive participation in the growth of the company in the form of stock option grants.  PACT Pharma is an ambitious cutting edge undertaking - we fully anticipate our company to become the world’s leader in personalized adoptive T cell therapies for cancer and therefore key to the future of cancer treatment. These positions are to be recruited for the Hayward, CA site.

Scientist/Sr. Scientist – Protein Chemistry/Engineering

The ideal candidate will be a highly experienced research scientist with a PhD in a relevant life science discipline with a track record of success in purifying and preparing protein samples for analysis by a variety of laboratory methods.  The successful candidate should be an expert in protein expression (including refolding routines) as well as purification methods, particularly column chromatography (affinity, ion-exchange, size-exclusion, hydrophobic interaction).  In addition, comprehensive experience of protein analytical techniques, including HPLC, ELISA, Flow Cytometry, SPR, calorimetry, and spectrophotometric analysis (UV, DLS, DSF, CD etc.) is required.  Direct experience in the formulation and handling of protein samples for automated processes would be highly advantageous.


The successful candidate will be a key member of the multi-disciplinary leadership team, led by the Sr. VP of Research and Product Development. She/he is expected to maintain rigor and quality of execution, documentation and timelines. The candidate should enjoy operating in an exceptionally dynamic and cooperative environment. She/he is highly dedicated to mentor team individuals, for motivating team success, and to contribute in a collegial manner to the entire company. She/he must be able to communicate clearly and concisely, both verbally and in the form of written reports, including drafting and review of protocols, SOPs, batch records and regulatory documentation to support clinical development.

The ideal candidate holds an advanced degree in chemical/engineering or relevant biological sciences and whose career focus has included ex vivo cell engineering with outstanding training in work with primary human cells. The role demands a highly goal-driven approach and the ability to focus on time-sensitive objectives.  The ideal candidate will have worked for 3+ years in industry with documented experience on protein engineering.