Scientist/Senior Scientist - DMPK - South San Francisco, CA | Biospace
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Scientist/Senior Scientist - DMPK

ORIC Pharmaceuticals, Inc.

South San Francisco, CA
Posted Date:
Position Type:
Full time
Job Code:
Required Education:
Areas of Expertise Desired:
Biochemistry, Chemistry, DMPK, Drug Discovery, Pharmacokinetics, PhD, Principal Scientist, Scientist,

Job Description

ORIC Pharmaceuticals, Inc. is a science-driven research organization devoted to identifying resistance mechanisms in cancer and discovering novel drugs that, in combination with existing treatments, provide long-term benefit to patients. ORIC was founded by a team of internationally recognized experts in oncology with a proven track record of discovering and marketing novel therapeutics.  The company is supported by investors with extensive experience in both drug development and the financing of life science companies.  The company is headquartered in South San Francisco, California.

We are seeking a highly skilled and motivated Scientist with expertise in Drug Metabolism and Pharmacokinetics to join ORIC’s Discovery team. The successful candidate will support pharmacokinetic and drug metabolism studies to enable discovery and development of small molecule drugs. Depending on the level of experience, the candidate may also serve as the DMPK project representative on drug discovery project teams and work closely with medicinal chemists to identify and solve the DMPK issues for the SAR molecules, or contribute to the clinical PK analysis function. The ideal candidate will be self-driven, highly organized, focused and enjoy working in a dynamic team environment.


•   Ph.D. degree in pharmacokinetics, drug metabolism, biochemistry, chemistry or other relevant fields with at least 3 to 5 years of relevant industry experience and good understanding of PK and ADME concepts
•   Hands-on experience with LC-MS/MS and extensive experience in the development of LC-MS/MS bioanalytical methods to support pre-clinical PK or metabolism studies
•   Ability to use Phoenix and other data management software
•   Knowledge of drug metabolism, biotransformation, experience in identification of in vivo and in vitro metabolites
•   Excellent oral and written communication skills
•   Excellent interpersonal skills and ability to work in a team environment
•   A strong fit with ORIC’s culture and core values of commitment to excellence, patient-centered and collaboration.  Must be resourceful, self-driven and enthusiastic with the ability to thrive in a dynamic start-up environment