Scientist, PK/PD Modeling at Vertex - San Diego, CA | Biospace
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Scientist, PK/PD Modeling at Vertex


San Diego, CA
Posted Date:
Position Type:
Full time
Job Code:
Required Education:
Areas of Expertise Desired:

Job Description

Vertex is a global biotechnology company that aims to discover, develop and commercialize innovative medicines so people with serious diseases can lead better lives. In addition to our clinical development programs focused on cystic fibrosis, Vertex has more than a dozen ongoing research programs aimed at other serious and life-threatening diseases.

Founded in 1989 in Cambridge, Mass., Vertex today has research and development sites and commercial offices in the United States, Europe, Canada and Australia. For four years in a row, Science magazine has named Vertex one of its Top Employers in the life sciences. For additional information and the latest updates from the Company, please visit

Vertex Pharmaceuticals, Inc. is seeking a highly motivated scientist for our DMPK group in San Diego, CA.  The successful candidate is required to have solid training in pharmacokinetics, and apply his/her knowledge and technical experience to address critical PK and PK/PD related issues to support the drug discovery and development process in multi-disciplinary team setting.
Key Responsibilities:
• Evaluate in vitro in vivo correlation in pre-clinical species to guide drug design and candidate selection in early discovery.
• Design PK and PK/PD experiments and develop mathematical models to elucidate PK/PD relationships in pre-clinical species
•Integrate pre-clinical data for human PK and dose prediction


Minimum Qualifications
•  Ph.D. in pharmaceutical sciences or a relevant field with 2+ years of experiences in PK and PK/PD modeling.
• Proficiency in WinNonlin/Phoenix is required; SimCYP and GastroPlus or other modeling and simulation software is desirable
• Familiar with Watson and bioanalysis with LC/MS/MS methods
• Excellent communication skills

Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, gender, age, religion, national origin, ancestry, disability, veteran status, genetic information, sexual orientation or any characteristic protected under applicable law. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.