DNS is seeking a PhD with a strong background in synaptic physiology. The researcher will investigate the role of regulators of memory formation in synaptic function and plasticity in support of our target discovery and drug development programs. The preferred candidate will have demonstrated ability to conduct creative and productive research in an academic or industry environment. The candidate will employ state-of-the art electrophysiological and imaging techniques to evaluate mechanisms of action for novel regulators of memory. A Ph.D. degree and two or more years of research experience are required for this position. Experience in hippocampal slice physiology using whole cell patch clamp recording and fluorescence imaging techniques is essential. The preferred candidate has a strong background in mechanisms of memory at the synaptic, cellular, and systems level. Some industry experience is desirable for this position.
The selected candidate will be working in a creative, fast-paced environment, interacting with scientists from diversified backgrounds, such as molecular biology, assay development, and behavioral pharmacology. The position demands team-oriented execution of time-dependent experiments. Thus, the candidate must have excellent interpersonal skills and must be organized with data collection, meeting presentations and composing study reports. Performs other related duties as required and assigned.
•PhD in Neuroscience, Pharmacology or related field.
•Two or more years of post-doctoral experience.
•Experience in brain slice physiology using patch clamp and/or optical recording techniques.
•Experience working in a drug discovery environment is desired.
•High level of initiative, independence, and ability to work unsupervised.
•Excellent interpersonal communication skills. Ability to effectively interact with an interdisciplinary team of molecular biologists, pharmacologists and behaviorists.
•Strong analytical and problem solving skills are expected.
•Proficient with scientific software applications (e.g., PClamp, MetaMorph).