Scientist - In vivo pharmacologist - Cambridge, MA | Biospace
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Scientist - In vivo pharmacologist

Pfizer Inc.

Cambridge, MA
Posted Date:
Position Type:
Full time
Job Code:
Required Education:
Bachelors Degree
Areas of Expertise Desired:

Job Description

About Pfizer

A career at Pfizer offers opportunity, ownership and impact. All over the world, Pfizer colleagues work together to positively impact health for everyone, everywhere. Our colleagues have the opportunity to grow and develop a career that offers both individual and company success; be part of an ownership culture that values diversity and where all colleagues are energized and engaged; and the ability to impact the health and lives of millions of people. Pfizer, a global leader in the biopharmaceutical industry, is continuously seeking top talent who are inspired by our purpose to innovate to bring therapies to patients that significantly improve their lives.

Role Description

Department Marketing Statement The Pfizer Inflammation & Immunology (I&I) research unit aims to develop novel therapeutics to treat autoimmune and inflammatory diseases. The successful candidate for this position will conduct pharmacology studies using in vivo animal model studies, ex vivo sample analysis and in vitro assays. The position is based in Kendall Square, Cambridge, MA but may require supporting studies at other Pfizer's sites as necessary. Job Focus Highly motivated individual to work in a challenging environment within the preclinical pharmacology group. As part of this team, this person will be supporting in vivo studies and analyzing samples obtained from these studies. Responsible for conducting and managing in vivo studies to determine the efficacy of both small molecule and Biotherapeutic approaches. The evaluation and development of new technologies, biomarkers and in vivo models are key components of this position.


* Plan and conduct of experiments in vivo studies in support of Inflammation & Immunology therapeutic portfolio
* Formulation of compounds and administration of drugs and experimental compounds by various routes
* Collection of blood and various tissues
* Ability to learn and conduct other animal-related techniques
* Ex vivo analysis of animal samples
* Maintaining well-organized records and documentation Data entry and analysis



* M.Sc. or B.Sc. degree in physiology, pharmacology, or related biological science
* B.Sc. degree with 6+ years or M.Sc. degree with 5+ years' experience
* Experience working with small laboratory animals, preferably in a biotech or pharmaceutical environment
* Well established hands-on experience with rodent in vivo dosing and handling techniques
* Understanding of immunology, cell biology or fibrosis
* Experience with animal models of inflammation is desirable
* Good organizational and communication skills, ability to focus attention to details
* A high degree of flexibility, and a willingness and ability to work as a team member
* Weekend or after hours work may be required
* Technical expectations
* Design and conduct experiments to support the mechanistic and disease biomarker discovery for in vivo models
* Planning, coordination and execution of in vivo and ex vivo pharmacology studies in rodent models
* Experience with small animal handling procedures, injections, oral dosing
* Experience in tissue dissection and tissue preparation for histology, RNA, and protein analysis
* Experience in molecular biology techniques such as ELISA, FACS, TLDA and RT-PCR, CBA and Luminex assays
* Analyzing and presenting data to individuals and in group settings

EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.