Scientist II (Biochemistry) - South San Francisco, CA | Biospace
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Scientist II (Biochemistry)

Mission Bio Inc.

South San Francisco, CA
Posted Date:
Position Type:
Full time
Job Code:
Required Education:
Areas of Expertise Desired:
Biochemistry, Genetics, Molecular Biology,

Job Description

   Mission Bio is a start-up developing innovative solutions in single-cell genomics to enable precision biology and translational research with the discoveries to impact patient care.  We are a small team that is growing rapidly, so this is an opportunity for talented, driven individuals to make a significant impact on the direction and success of an exciting young company. If you are a collaborative, curious, hardworking professional who thrives in a fast-paced, dynamic, supportive environment, we would love to meet you. Mission Bio offers a comprehensive benefits and wellness package to eligible employees.

   We are looking for a highly motivated and qualified individual to help us achieve our goal of launching innovative new technologies for characterizing heterogeneous cell populations at the single cell level.  The successful candidate will lead the expansion of our single-cell sequencing approach across multiple applications and sample types. The candidate will develop novel molecular biology protocols and reagents at the core of a new approach to single-cell genomics.


Job Duties
•   Establish protocols for cell or nuclear isolation from tumor biopsies, FNA, fresh frozen and FFPE samples.
•   Evaluate the compatibility of different sample collection and preservation approaches with our single-cell sequencing approach.
•   Optimize nucleic acid isolation for different types of clinical samples.
•   Investigate sample specific NGS library preparation methodologies.
•   Interface with outside vendors for sample sourcing and cell sorting as needed.
•   Contribute to technical discussions and collaborate with engineering and analytical groups.

•   PhD in molecular biology, biochemistry, genetics, or a related discipline.
•   3-5 years industry experience required.
•   Extensive molecular biology experience is required. Examples include: nucleic acid isolation and amplification, primer design, and sequencing library preparation.
•   Record of developing novel molecular biology and biochemistry protocols.
•   Extensive experience working with liquid and solid tumor samples.
•   Ability to prepare single-cell suspensions from various sample types.
•   Experience with DNA isolation from FFPE and other clinical samples a plus.