Scientist I (NCI) - Frederick, MD | Biospace
Get Our FREE Industry eNewsletter

Scientist I (NCI)

Leidos Biomedical Research, Inc.

Frederick, MD
Posted Date:
Position Type:
Full time
Job Code:
Required Education:
Areas of Expertise Desired:

Job Description

The Strategic Pilots Incubator (SPI) is responsible for the development and management of a portfolio of exploratory projects that are inherently multidisciplinary that impact cancer research and treatment. Projects aim to analyze the complex interactions in tumor cells and tissues and model systems, blending the best of new physics and engineering based advances with established technologies enabling new opportunities for deeper understanding of tumor biology and cancer progression.  Using the latest tools in understanding human performance under stressful conditions can be used to understand and hopefully mitigate the toxic effects of cancer therapy for the patient.

We are currently recruiting for an experienced biomedical engineer or scientist to support a newly established High Content Technology Facility at the Frederick National Laboratory for Cancer Research. The new facility will revolve around tissue and single cell analysis with the newly acquired Helios Imaging Mass Cytometer. We are looking for a self-motivated and proactive individual interested in a cutting-edge and developing technology. The successful candidate will be taking on a pivotal role in the set up and running of the new high content laboratory. Subsequent to onsite training, candidates will be expected to be skilled in CyTOF imaging mass cytometry and to develop and implement different applications of this technology.

The Scientist will be responsible for:
Setting up and technically validating an imaging mass cytometer at FNLCR
Developing software and macros for running instrumentation
The daily management and operation of the cytof
Establishing standardized operating procedures (SOP)
Assisting scientists in experimental design and setup
Setting up and maintaining an antibody bank and reagent base
Data analysis


To be considered for this position, you must minimally meet the knowledge, skills, and abilities listed below:
Possession of a PhD degree from an accredited college/university according to the Council for Higher Education Accreditation (CHEA) in Biomedical Engineering, Physics, Chemistry, or related field or eight (8) years equivalent experience in lieu of degree
Foreign degrees must be evaluated for U.S. equivalency
No work experience beyond the doctorate education is required for appointment at this level; however, some candidates may have had one or more years of postdoctoral research and training
Strong background in analytical chemistry and digital histopathology
Experience with immunocytochemistry (ICC) and immunohistochemistry (IHC) techniques
Experience in microscopy and image acquisition/analysis
Proficiency with Microsoft Office including Excel
Ability to learn new techniques and troubleshoot assays
Must be able to obtain and maintain a security clearance
Candidates with these desired skills will be given preferential consideration:
Experience with antibody assay development
Prior experience with mass cytometry or mass spectrometry
Proficiency in R and/or Python programming
Experience with tissue and blood sample handling