Scientist I (Biochemistry) - South San Francisco, CA | Biospace
Get Our FREE Industry eNewsletter

Scientist I (Biochemistry)

Mission Bio Inc.

South San Francisco, CA
Posted Date:
Position Type:
Full time
Job Code:
Required Education:
Areas of Expertise Desired:
Biochemistry, Scientist,

Job Description


   Mission Bio is a start-up developing innovative solutions in single-cell genomics to enable precision biology and translational research with the discoveries to impact patient care.  We are a small team that is growing rapidly, so this is an opportunity for talented, driven individuals to make a significant impact on the direction and success of an exciting young company. If you are a collaborative, curious, hardworking professional who thrives in a fast-paced, dynamic, supportive environment, we would love to meet you. Mission Bio offers a comprehensive benefits and wellness package to eligible employees.


   We are looking for a highly motivated and qualified individual to help us achieve our goal of launching innovative new technologies for characterizing heterogeneous cell populations at the single cell level.  The successful candidate will develop targeted sequencing approaches to expand our single-cell sequencing approach to additional indications and sample types. The candidate will develop novel molecular biology protocols and reagents at the core of a new approach to single-cell genomics.

Job Duties

•   Enable application of single-cell genomics to additional clinical indications.
•   Optimize nucleic acid isolation from different types of clinical samples.
•   Develop novel barcoding strategies for different aspects of single-cell biology.
•   Research and demonstrate feasibility of new NGS library preparation methodologies.
•   Streamline user-facing protocols to reduce hands-on-time and assay robustness.
•   Interface with outside vendors and internal manufacturing teams.
•   Contribute to technical discussions and collaborate with engineering and analytical groups.



•   PhD in molecular biology, biochemistry, genetics, or a related discipline.
•   3-5 years industry experience required.
•   Extensive molecular biology experience is required. Examples include: nucleic acid isolation and QC, restriction digests, primer design, PCR, RT-PCR and whole genome amplification.
•   Experience with different NGS library preparation methodologies a must.
•   Experience with multiplex PCR highly desired.
•   Ability to analyze and visualize NGS data considered a big plus.
•   Record of developing novel molecular biology and biochemistry protocols.
•   Strong ability to document experiments and troubleshoot protocols.
•   Demonstrated ability to work effectively and cooperatively in a team environment.