Scientist I - IF and IHC - Gaithersburg, MD | Biospace
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Scientist I - IF and IHC

MedImmune, LLC

Gaithersburg, MD
Posted Date:
Position Type:
Full time
Job Code:
Required Education:
Masters Degree
Areas of Expertise Desired:

Job Description

Gaithersburg, Maryland, United States
Job reference: R-014051
Posted date: Sep. 18, 2017

Scientist I - IF and IHC,Gaithersburg, MD

MedImmune is the worldwide biologics research and development arm of AstraZeneca. Here, you’ll have the opportunity to make a difference in people’s lives every day. As one of the world’s premier biotechnology companies, our mission is centered on delivering life-changing products that advance world health, and help fight and cure disease.  As a Scientist I, you’ll play a pivotal role in channeling our scientific capabilities to make a positive impact on changing patients’ lives.

We’re constantly pushing the boundaries of science to deliver life-changing medicines to patients, with a passion for discovery and a pipeline to show for it. We’re pioneering innovative research and exploring novel pathways across key therapeutic areas including oncology, respiratory, inflammation and autoimmunity, cardiovascular and metabolic disease, and infection and vaccines. And we’re industry-leading in immunology, protein engineering and translational science.

We offer a unique and strong collaborative network as part of the AstraZeneca family, as together we explore synergies between small and large molecules. MedImmune has a dynamic environment that fosters collaboration and innovation. We attract top minds, and we nurture and build top talent.


Organize, coordinate and develop technical components of new methodologies, staining techniques and antibodies for immunofluorescent (IF) and immunohistochemistry (IHC). To include single and multi-plex assay.  Work directly with senior pathologist to optimize assays for research and early clinical work.


  • Leads the team in developing new multiplex and single plex IF and IHC assays
  • Keeps abreast of new developments in the field of IF and IHC and pursue self development programs.
  • Initiates development and deployment of new antibodies in the laboratory based on scientific need.
  • Works directly with senior pathologists to analyse data and determine next steps.
  • Organizes tasks on a daily basis to coordinate the workflow of developmental and validation work being done in the laboratory.
  • Continuously updates and oversees current antibodies, and investigates for improved methods of staining with current antibodies, as well as different titers, etc.
  • Identifies variations and methods to correct problem areas and control the immunohistochemistry area's productivity and utilization of time and workflow.
  • Oversight for scientific and technical conduct of technically demanding immunohistochemical and tissue/cell based experiments and biomarker development strategies.
  • Makes detailed observations, analyzes data and interprets results and demonstrates scientific rigor in assessing own data and that of others.
  • Effectively presents results at internal meetings and external scientific meetings.
  • Conducts complex research projects and typically conducts more than one project at a time.
  • Work is performed with limited direction; has latitude in determining scientific objectives.
  • Conducts research focused on the translational aspects of drug development in collaboration with senior pathologist and other individuals within the R&D department.
  • Prepares precise technical reports, summaries, protocols, quantitative analyses and maintains appropriate documentation.
  • Has demonstrated leadership.



PhD with 0-3 years experience or MS with 8-10 years experience and BS with 10-13 years experience.    


Minimum of 1-7 years experience to include IF assay development and analysis


Strong Immunohistochemistry and immunofluorescent skills

Experience in immunofluorescent analysis

Leadership skills.

Proven project management skills.

Understanding of the drug development process for biologicals.

Strong understanding of immunology.

Basic understanding of pharmacokinetics and PK/PD relationships.


Attention to detail.

Good time management and organization – capable of working with minimal direction. Proven good communication and global working skills.

Excellent team working skills.

Next Steps – Apply today!

To be considered for this exciting opportunity, please complete the full application on our website at your earliest convenience – it is the only way that our Recruiter and Hiring Manager can know that you feel well qualified for this opportunity.  If you know someone who would be a great fit, please share this posting with them.

AstraZeneca is an equal opportunity employer. AstraZeneca will consider all qualified applicants for employment without discrimination on grounds of disability, sex or sexual orientation, pregnancy or maternity leave status, race or national or ethnic origin, age, religion or belief, gender identity or re-assignment, marital or civil partnership status, protected veteran status (if applicable) or any other characteristic protected by lawAstraZeneca only employs individuals with the right to work in the country/ies where the role is advertised.