Scientist - Early Upstream - Alachua, FL | Biospace
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Scientist - Early Upstream


Alachua, FL
Posted Date:
Position Type:
Full time
Job Code:
Required Education:
Areas of Expertise Desired:
Biology, Development, Engineering, Process, Process Development, Scientist,

Job Description

Applied Genetic Technologies Corporation (AGTC) is a clinical stage biotechnology company dedicated to developing novel gene therapies for ophthalmic and respiratory-based diseases. AGTC has multiple candidate gene therapeutics in or entering human clinical trials and is seeking a full-time Scientist for Early Upstream Process Development activities.

Reporting Relationship:
•   The Scientist, Early Upstream Process Development will report directly to the Executive Director, Process Development

Job responsibilities will include, but are not limited to, the following.
•   Independently plan and execute experimental protocols
•   Cell line optimization, adaptation, screening, selection and characterization for AAV production
•   Evaluation of media formulations and process conditions on viral vector production and quality
•   Apply statistical analyses to experimental design and data sets
•   Document research with SOPs and internal reports as appropriate
•   Manage a team of 2-4 Research Associates or Scientitsts
•   Represent the company at scientific meetings and present data where applicable


The successful candidate will meet the following requirements.
•   A Ph.D. in a biological science or engineering with 5-10 years of experience in an academic or industrial setting
•   Extensive hands-on mammalian cell culture experience in the production of biologics, preferably in both adherent and suspension formats
•   Strong molecular biological skills encompassing protein, RNA and DNA analyses by conventional and/or advanced techniques
•   Ability to identify and adapt new technologies to the production and characterization of viral vectors
•   Previous experience with viral vaccines, viruses or viral vectors is highly desired

AGTC offers a competitive compensation commensurate with education and experience, including salary, benefits, and company equity.  AGTC is an EOE and maintains a drug-free workplace.