Scientist, Drug Discovery - Waltham, MA | Biospace
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Scientist, Drug Discovery

AstraZeneca Pharmaceuticals LP

Waltham, MA
Posted Date:
Position Type:
Full time
Job Code:
Required Education:
Masters Degree
Areas of Expertise Desired:

Job Description

Location: Waltham,
United States
Job reference: R-012917

Posted date: Sep. 21, 2017

Job Description:

At AstraZeneca we work together across global boundaries to make an impact and find answers to challenges. We do this with the upmost integrity even in the most difficult situations because we are committed to doing the right thing. We continuously forge partnerships that help pursue world-class medicines in new ways, combining our people’s exceptional skills with those of people from all over the globe. As a Scientist in Cancer Cell Biology-Drug Discovery, you will become a key member of a dynamic and collaborative in vitro biology team responsible for applying molecular and cellular approaches to progress cancer drug discovery projects.

We are global, innovation-driven, integrated biopharmaceutical company. Our mission is to make a meaningful difference to patient health through great medicines that bring benefit for patients and add value for society. We discover, develop, manufacture and market prescription medicines for important areas of healthcare, which include some of the world’s most serious illnesses: cancer, cardiovascular disease, respiratory, inflammation, and autoimmune diseases. We are driven by a shared goal to make a positive impact on the lives of patients with these serious diseases.

In addition to our passion for the discovery of innovative new medicines, we understand the importance of flexibility in our work-life environment and we offer a wide variety of benefits, services and programs that provide our employees the resources they need to pursue not only their work goals but also their life goals. We are dedicated to building strong research teams that embrace the diversity of talents of team members and allow the larger group to grow and learn together to accomplish our collective goal to improve human health.

Main Duties and Responsibilities

Your primary responsibility is to develop and run cell-based assays to identify early-stage lead molecules, explore drug mechanism of action and to further understand target biology. Your efforts will ultimately lead to the identification of drug candidates and the generation of compelling preclinical data packages to progress promising drug discovery projects towards clinical development. You will be expected to maintain cell lines in tissue culture, develop and perform cell-based assays including, but not limited to, cell growth, survival, cell cycle, apoptosis and specific mechanism of action assays and perform additional cell techniques such as western blotting. You will be responsible for working closely with project teams to meet goals in a timely manner.

Major Responsibilities

  • Maintaining mammalian cell lines in tissue culture
  • Developing, characterizing, implementing, running and troubleshooting medium throughput cell-based screening assays
  • Performing and interpreting mechanism of action and cell biology studies
  • Generating and maintaining clear experimental records
  • Organizing and clearly presenting experimental results to the project team


Minimum Requirements

  • Bachelors or Masters degree in Cell Biology or equivalent
  • Demonstrated proficiency in data processing and data management
  • A positive, collaborative attitude and natural desire to learn and improve

    Preferred Background

  • Cancer cell biology
  • Drug discovery experience at biotech or pharmaceutical company
  • Familiarity with multiple assay platforms/screening technologies
  • 1-3 years of assay development experience

Next Steps – Apply today!

To be considered for this exciting opportunity, please complete the full application on our website at your earliest convenience – it is the only way that our Recruiter and Hiring Manager can know that you feel well qualified for this opportunity. If you know someone who would be a great fit, please share this posting with them.

AstraZeneca is an equal opportunity employer. AstraZeneca will consider all qualified applicants for employment without discrimination on grounds of disability, sex or sexual orientation, pregnancy or maternity leave status, race or national or ethnic origin, age, religion or belief, gender identity or re-assignment, marital or civil partnership status, protected veteran status (if applicable) or any other characteristic protected by law.