Scientist, Cancer Biology - Bothell, WA | Biospace
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Scientist, Cancer Biology

Seattle Genetics, Inc.

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Location:
Bothell, WA
Posted Date:
9/4/2017
Position Type:
Full time
Job Code:
1808
Salary:
Required Education:
Doctorate/PhD
Areas of Expertise Desired:

Job Description

Summary:

Seattle Genetics is seeking a highly motivated research scientist with strong translational oncology research expertise.  Seattle Genetics is an established leader in the development of tumor-directed antibody-drug conjugates (ADCs) and is expanding into therapeutic approaches involving immune modulation. These include co-administration of ADCs with approved immuno-oncology agents (e.g. checkpoint inhibitors), development of novel immuno-oncology agents, and evaluation of existing ADCs in autoimmune and inflammatory disorders. The scientist will perform cross-functional research to advance the company's drug development pipeline and elucidate the mechanisms of disease biology, and drug interactions with the tumor microenvironment.

Responsibilities:

   
        
  • Design, perform, and document cell biology experiments to validate targets for antibody-based therapeutics
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  • Identify new cancer drug targets and advance antibody-based drug projects from inception to clinical development
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  • Develop novel assays and experiment systems to mimic the disease biology and facilitate translation between research settings and clinical trials
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  • Contribute to study design and data interpretation, and present work to various project teams
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  • Articulate and present scientific work at cross-functional group and national meetings
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Requirements

Qualifications:

  • Ph.D. in Cancer Biology, Cancer Genetics, Immunology, Genomics, Cell Biology or related fields in cancer research. Candidates with knowledge in acute myeloid leukemia are encouraged to apply
  • Ideal candidates will have 2+ years successful post-doctoral research experience, as demonstrated by a strong publication record
  • Technical expertise in multicolor flow cytometry, cell biology assays and tissue culture techniques ( e.g., engineering cell lines), biochemical methods to investigate signal transduction pathway ( e.g., western blotting and microscopy), and/or rodent cancer models
  • Familiarity with cancer genome databases and large scale data analysis and data mining. Experience with RNA-sequencing is a plus
  • Candidates must have good interpersonal skills to work collaboratively in a team environment and excellent oral and written communication skills
  • Creative, independent, well organized, collaborative, and solution-oriented

Seattle Genetics is an equal opportunity employer. All qualified applications will receive consideration for employment without regard to race, color, religion, sex, national origin, protected veteran status, or disability status.