Scientist, Assay Development - Menlo Park, CA | Biospace
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Scientist, Assay Development

Nuredis, Inc.

Location:
Menlo Park, CA
Posted Date:
8/16/2017
Position Type:
Full time
Job Code:
Salary:
Required Education:
Doctorate/PhD
Areas of Expertise Desired:

Job Description

About Nuredis
Nuredis, Inc. discovers and develops small molecule therapies for a group of inherited neurodegenerative and neuromuscular diseases, aiming to treat the cause of disease rather than just managing symptoms. Nuredis was founded in 2016 based on technology licensed from Stanford, with facilities in Menlo Park. Nuredis is looking for a self-driven candidate who will be an integral member of our dynamic and highly motivated research team, to make significant contributions to therapeutic development.

Job Description
The current position to be filled is Scientist, Assay Development.  The candidate will be expected to develop and perform in vitro assays such as ELISA and cell-based assays to determine therapeutic efficacy of small molecules in our therapeutic pipeline. In addition, the candidate will be tasked to develop new assays to measure biochemical markers of therapeutic effects to be used for clinical trial purposes. The work scope includes developing, validating, and performing ELISA assays, running cell-based assays and DNA-based assays to evaluate drug efficacy. Setting up SOP, documenting experimental processes and generating reports will also be key duties.

Requirements

Minimum Qualifications
•   Ph.D. in Molecular Biology, Biochemistry, Cell Biology, Genetics, Chemistry Neurobiology or related fields with 5+ years of post-graduate experience in developing and/or validating protein assays such as ELISA and cell-based assay development
•   Ability to design experiments and think independently with minimal supervision
•   Ability to work as a productive member in a dynamic and highly collaborative team; high level of energy, enthusiasm and initiative, good communication skills
•   Must be legally authorized to work in the United States

Additional Qualifications
Candidates with direct experience in the following areas will be given priority.
•   Experience in developing and performing ELISA assays to evaluate small molecule drug candidates; specifically, establishing assay parameters such as specificity, selectivity, quantification limits (LLOQ), linearity, and reproducibility
•   Experience in overexpression and purification of large intracellular proteins from mammalian cell culture
•   Experience in making monoclonal antibodies
•   Experience in handling human blood samples
•   Experience in animal studies
•   Experience in fields of neurobiology or neurodegenerative diseases
•   Basic statistical analysis of data
•   2+ years of work experience in Biotech or Pharma industry is preferred

Application Instructions
To apply, please email your cover letter and resume to HR@nuredis.com, with the subject line “Nuredis Application: Scientist, Assay Development”