Scientist - Cambridge, MA | Biospace
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Scientist

Amgen

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Location:
Cambridge, MA
Posted Date:
9/22/2017
Position Type:
Full time
Job Code:
R-43682
Salary:
Required Education:
Doctorate/PhD
Areas of Expertise Desired:

Job Description

Amgen is currently seeking a Scientist in our Drug Product Technologies Department with a strong scientific background in Protein Biochemistry.

This position will identify current gaps in Amgen's tools and technology to advance our understanding of protein:protein and protein:surface interactions. Working in a science based organization, the successful candidate will actively contribute to the evolution of our understanding of the molecular drivers of aggregation and surface interactions. This individual will be involved in providing unique solutions to these challenging protein interactions.  The optimization of protein therapeutics for stabilization towards alternative modes of delivery and storage is of critical importance in the development of human therapeutics. Cross-functional and cross-team collaborations are expected.

Responsibilities include:
* An opportunity for a highly motivated and creative candidate to develop, advance and apply protein biochemistry/polymer technologies to drug delivery challenges

* Drive continuous improvement in our knowledge of protein behavior through technological innovation and application of experimental findings

* Responsible for development and exploration of new technologies for different modalities such as fusion proteins, Mab fragments, RNA based drugs

* Deliver progress reports, presentations, expectations include both internal and external presentation of scientific data with an eventual external publication/patent track record.
* Participation in global cross-functional teams working effectively in a highly matrixed team environment to enhance our understanding of protein behavior

Requirements

Basic Qualifications:

Doctorate degree
OR
Master's degree and 4 years of scientific experience
OR
Bachelor's degree and 6 years of scientific experience

Preferred Qualifications

* Advanced degree in Pharmaceutics, Biotechnology, Biochemistry, Physical Biochemistry or related discipline with a minimum of 2-4 years of Post-Doctoral experience in Protein Biochemistry

* Advanced knowledge and hands on experience in Bio-physical and Molecular Biology techniques

* Experience in developing and implementing emerging technologies
* Strong independent problem solving and communication skills
* Demonstrated background in protein characterization, stability and experience in development of parenteral control release delivery systems is a plus
* Publication background commensurate with Protein Biochemistry.
* Advanced understanding of predictive methods, protein stability and solubility

* Demonstrated background in modeling and prediction of protein:protein interactions and protein behavior
* Demonstrated ability to learn and act on dynamic information at a rapid pace.