DNS’s Vertebrate NeuroGenomics group focuses on the identification of genes and gene networks central to memory formation and its underlying cellular plasticity. Key regulatory proteins will become targets for small molecule drug discovery.
We are seeking a PhD with a background in behavioral neuroscience. The scientist will lead pharmacological and genomic studies in support of drug target and lead discovery. The preferred candidate will have demonstrated the ability to conduct creative and productive research and will implement in vivo behavioral techniques in a drug discovery environment. A Ph.D. degree in Behavioral Neuroscience or Pharmacology, and a minimum of four years of industrial research experience are required for this position. Candidates with strong post-doctoral experience in the field of cognitive neuroscience with particular emphasis on learning and memory are preferred for this position.
This position offers significant opportunity to develop scientific and managerial skills in a biotechnology environment. The selected candidate will work in a creative, fast-paced environment, interacting with scientists from diversified backgrounds, such as high-throughput drug screening, bioinformatics, molecular Neuroscience and ADMET/PK. The position demands team-oriented execution and management of time-dependent experiments. Thus, the candidate must have excellent interpersonal skills and must be experienced in contributing to project teams.
•Participate in company wide target and drug discovery process.
•Characterize candidate targets for cognition and neurodegenerative disease.
•Establish rodent models of Neurodegenerative disease.
•Establish in vivo efficacy and pharmacodynamic properties of novel memory enhancers.
•Manage research associates.
•Keep meticulous records of experiments and results.
•Prepare project reports.
•Ensure effective internal communication to project teams and senior management.
•PhD in Behavioral Neuroscience or Pharmacology.
•A minimum of four years industry experience in Behavioral Pharmacology.
•Hands on experience in assays of cognition with particular emphasis on learning and memory.
•Experience in in vivo genetic techniques, including stereotactic surgery.
•Experience in Pharmacodynamic and Pharmacokinetic studies in Rodents.
•Experience working in project teams within the pharmaceutical industry.
•Experience in histological techniques and microscopy.
•Experience in managing associate scientists.
•High level of initiative, independence, and ability to work unsupervised.
•Candidates with a demonstrated background and interests in studies of learning and memory and neurodegenerative disease are preferred for this position.