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Scientist

DiscoveRx Corporation

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Location: South San Francisco, CA Posted Date: 4/29/2013 Position Type: Full time Job Code: 021413 Required Education: Doctorate/PhD Areas of Expertise Desired: Biochemistry
Cell Biology
Cell Culture
Laboratory
Oncology
Postdoctoral

Description

A Scientist position is available for a highly motivated and innovative scientist with strong technical and collaborative skills to join BioSeek, a division of DiscoveRx. The successful candidate will be responsible for conducting scientific research in developing novel primary human cell-­-based model systems relevant to oncology and fibrosis (epithelial and fibroblast cell biology). The ideal candidate is expected to play a pivotal role in expanding our proprietary BioMAP® platform technology (www.biomapsystems.com) to support our clients’ oncology programs and pipelines. The candidate should excel in innovative thinking, scientific excellence, expertise in primary human cell culture, team spirit, creativity and enthusiasm for the drug discovery process. As part of the BioSeek-DiscoveRx team, the successful candidate will collaborate with talented and dedicated colleagues and interface with our Pharma and Biotech-based clients across the globe.

POSITION DUTIES AND RESPONSIBILTIES:
• Work in collaboration with supervisor and other scientific staff to develop and optimize new primary human cell models in the areas of oncology (human cell lines) and fibrosis (epithelial cells and fibroblasts) encompassing technical design and execution of assays, data analysis and reporting, literature reviews and trouble-­-shooting.
• Lead analysis and interpretation of data, prepare and deliver clear and concise oral and written presentations for senior management and pharmaceutical partners.
• Publication of study results and presentation of findings at multi-disciplinary project team meetings and scientific conferences.
• Work within cross---functional teams to achieve group and company goals within defined timeframes and resources.
• Maintain mastery of relevant and changing scientific literature and incorporate current knowledge and technologies into the BioMAP platform.
• Other duties as assigned.

Requirements

POSITION REQUIREMENTS:
• The ideal candidate must have strong expertise in primary cell culture, cell biology, biochemical signaling, and analytical skills including in depth knowledge of cancer biology and anti-cancer biologics.
•  The successful candidate should have a strong ability to independently design and execute cell-based experiments using a variety of techniques including primary cell culture, immunoassays, immunohistochemistry, flow-cytometry and basic molecular biology techniques.
• Superior presentation, communication and analytical skills with the ability to effectively communicate and collaborate in a global environment, with a diverse range of people and job functions.
• Critical thinking, systematic problem solving skills, and good operative skills in the design and conduct of scientific experiments and interpretation of results.
• Reliability, pro-active hands-on attitude and the ability to independently implement research projects are another important success factor.
• Candidate should be organized, self-motivated and a team player, consensus builder with a creative mind, able to establish and implement innovative business solutions and concepts.
• Methodical but with a sense of urgency to meet goals on time and within budget.

MINIMUM EXPERIENCE AND/OR EDUCATION REQUIRED:
• Ph.D. in the life sciences, with a minimum of 2 years of postdoctoral experience preferably in the pharmaceutical or biotech industries.
• Comprehensive knowledge of human cell-based assay and cell culture techniques, including proficiency and experience with human cancer cell types (epithelial cells and fibroblasts).
• Strong track record in publishing and presenting scientific findings.

PHYSICAL DEMANDS:
• Laboratory setting

WORKING CONDITIONS:
• BSL2 laboratory setting
• Potential for exposure to human tissues and fluids
• Able to work flexible schedule

Our employees are the key to our company’s success. We demonstrate our commitment to our employees by offering a comprehensive benefits package including medical, dental, and vision insurance, paid time off, 401k, health care and dependent care flexible spending accounts as well as other benefits. Qualified candidates should submit a resume with cover letter to jobs@discoverx.com and reference job code DRx003-2013 in the subject line.

About BioMAP Systems
BioMAP® Systems incorporate predictive primary human cell-based disease models that generate uniquely informative activity profiles of each potential drug, assisting in the selection and development of new drug candidates. For more information on BioMAP, visit www.biomapsystems.com.

About DiscoveRx Corporation
Founded in 2000, DiscoveRx is a privately held, venture-backed company headquartered in Fremont, California, with additional offices in San Diego, California and Birmingham, England. The Company pioneered the use of ß-galactosidase enzyme fragment complementation (EFC) in HitHunter® biochemical and PathHunter® cell based assays for discovery research. In addition to the EFC platform, DiscoveRx also holds extensive intellectual property for its second core technology, an in vitro binding assay platform called KINOMEscan®. Utilizing these two proprietary platforms, DiscoveRx has developed and commercialized industry leading panels of GPCR, Kinase, and NHR assay solutions for drug discovery research. Many of DiscoveRx's innovative solutions have been widely adopted in pharmaceutical, academic and biotechnology laboratories worldwide. For more information, visit www.discoverx.com




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