Located in Boston and the surrounding communities, Dana-Farber Cancer Institute brings together world renowned clinicians, innovative researchers and dedicated professionals, allies in the common mission of conquering cancer, HIV/AIDS and related diseases. Combining extremely talented people with the best technologies in a genuinely positive environment, we provide compassionate and comprehensive care to patients of all ages; we conduct research that advances treatment; we educate tomorrow's physician/researchers; we reach out to underserved members of our community; and we work with amazing partners, including other Harvard Medical School-affiliated hospitals.
A full-time position is available for a highly motivated senior research technician to examine translational aspects of this disease. The laboratory uses a variety of biochemical, cell biology, and translational approaches to identify new therapeutic targets and develop preclinical models. The position offers the opportunity to eventually lead research efforts along with responsibility for high-throughput screening and routine laboratory tasks. This highly integrated goal-oriented Center provides an unprecedented opportunity to change the way anti-cancer therapeutics are discovered and developed. For more information please visit our website at www.bingcenterforwm.org
Identification and validation of survival pathways and associated rational therapeutic targets for WM
Previous experience in mammalian cell culture, Western blotting, immuno-precipitation, and immuno-fluorescence staining
Ability to do ELISA and flow cytometry
Analysis of cell viability including MTT assay and apoptosis assay
Basic molecular biology techniques including DNA/RNA/protein isolation, molecular cloning, and sequencing
Quantitative RT-PCR, AS-PCR, and MSP-PCR
Synthesis of constructs utilizing genomic and cDNA clones
Requirements of Transfection, knockdown using siRNAs and shRNA's is a plus
Animal model technique including mouse handling and genotyping is a plus.
BS/MS in biological sciences or equivalent; ALAT certification is desirable.
A minimum of 2-4 years research experience in academic and/or pharmaceutical/biotech environment.
Ability to work within a team environment.
Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other groups as protected by law.