Research Technician - Biostats - Boston, MA | Biospace
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Research Technician - Biostats

Dana-Farber Cancer Institute

Boston, MA
Posted Date:
Position Type:
Full time
Job Code:
Required Education:
Bachelors Degree
Areas of Expertise Desired:
Academic, Biology, Biology Research, Biomedical, Cancer, Cell, Cell Biology, Cell Culture,

Job Description

Located in Boston and the surrounding communities, Dana-Farber Cancer Institute brings together world renowned clinicians, innovative researchers and dedicated professionals, allies in the common mission of conquering cancer, HIV/AIDS and related diseases. Combining extremely talented people with the best technologies in a genuinely positive environment, we provide compassionate and comprehensive care to patients of all ages; we conduct research that advances treatment; we educate tomorrow's physician/researchers; we reach out to underserved members of our community; and we work with amazing partners, including other Harvard Medical School-affiliated hospitals.

This position will assist scientists in performing scientific research, development and/or clinical tasks of varying complexity. In general, this position will assist in the set up, operation and maintenance of laboratory instruments and equipment, monitoring experiments, making observations and calculating and recording results.

The principal mission of the Center for Cancer Evolution (CCE) is to develop and validate mathematical modeling strategies of tumor evolution and treatment response, and eventually utilize these strategies to identify best therapeutic intervention. We will investigate the treatment response of cancer cells and their microenvironment, develop novel mathematical frameworks describing the evolutionary dynamics of tumor progression and treatment response that are parameterized using the experimental systems, and predict and validate optimum intervention strategies that will ultimately be implemented as prospective clinical trials. The CCE is looking for a highly motivated laboratory research technician to join the CCE and work on a variety of cancer types. The focus of this individual's work will be the experimental arm of the CCE. Responsibilities will include evaluating new therapeutic targets, experimentally validating theoretical models, characterizing cell and cell line properties, performing single cell lineage tracing experiments and analyzing clinical cancer tissue samples. Additional duties include lab maintenance and organization as well as methods and results documentation.


Work will include among others delivery of medicines, marking responses and performing laboratory follow-up experiments on findings from these experiments. This individual will work with a team of research fellows and other scientists to perform cutting-edge research with potential impact on cancer treatment. Excellent organizational and communication skills, ability to work within a team, flexibility and responsibility are all key for this position.

Specific duties would include:

  • Culturing of cell line models
  • Performing drug testing of cell line models in cell culture.
  • Extraction and analysis of protein, DNA and mRNA from isolated materials
  • Evaluation of effects of specific therapies in model system through immunoblotting, staining and other proteomic experiments
  • Using general lab equipment
  • Data analysis and recording of results electronically and in a lab notebook
  • Prepare and write-up methods and procedures for publications
  • Prepare and maintain database of results
  • Working closely with a scientist who will serve as direct supervisor and mentor
  • Co-operating with a team of experimental and computational scientists
  • Managing ordering and stocking of laboratory supplies
  • Ability to work on a flexible schedule
  • Set up, adjust, calibrate, clean, maintain and troubleshoot equipment.
  • Clean, maintain and prepare supplies and work areas and may be responsible for ordering of supplies. Collaborates with Purchasing and may be responsible for negotiating with vendors.
  • Conduct standardized biological, microbiological or biochemical tests and laboratory analyses, including the collection of information and samples from organic substances, such as blood, drugs, and animals.
  • Isolate, identify and prepare specimens for examination.
  • Analyze experimental data and interpret results to write reports and summaries of findings, including grant preparation and presentations, and look for opportunities to co-author publications. May be expected to participate in formal and information presentations of results to staff.
  • Participate in grant application process and manuscript preparation as required.
  • Maintains detailed notebook of all work-related activities.
  • Monitors laboratory work to ensure compliance with Environmental Health and Safety information as well as the standard operation procedures specific to each laboratory.
  • Expected to provide intellectual and interactive commitment to position by keeping up with appropriate literature and research publications.
  • May be responsible for the development, modification and improvement of standard operating procedures.
  • Uses computers, computer-interfaced equipment, robotics or high-technology applications to perform work duties.

We are looking for an enthusiastic and capable individual with a BA or BS degree in a related field. Preference will be given to those with laboratory experience in molecular and cellular biology. Mentorship and training will be provided to individuals from center scientists. Experience in cell culture, and with immunoblotting are desirable. In addition to technical and scientific knowledge, this individual should have good organizational, interpersonal, and oral and written communication skills.

  • Bachelor's Degree required with a major in a related field.
  • Knowledge of information and techniques related to either biology, chemistry, or medicine is preferred.
  • Must have excellent communication skills (written and verbal) and be able to work with a wide variety of faculty and staff.
  • Ability to analyze information and use logic to address work-related issues and problems.
  • Must have attention to detail and be thorough in completing work tasks.
  • Ability to work within a team environment.

Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other groups as protected by law.