Research Associate/Sr Research Associate - South San Francisco, CA | Biospace
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Research Associate/Sr Research Associate

ORIC Pharmaceuticals, Inc.

South San Francisco, CA
Posted Date:
Position Type:
Full time
Job Code:
Required Education:
Bachelors Degree
Areas of Expertise Desired:
Assay Development, Cell Biology, Cell Culture, Elisa, Flow Cytometry, Molecular Biology, PCR,

Job Description

ORIC Pharmaceuticals is a privately-held company dedicated to discovering and developing novel therapies for treatment-resistant cancers.  While recent advances with targeted therapeutics have extended prognoses in many disease settings, cancers often develop resistance to current drugs and relapsed patients lack further treatment options.  The company has assembled a world-class scientific team dedicated to the discovery of therapies that can meaningfully improve clinical outcomes for these patients.  ORIC was founded by two world-class experts in oncology who have strong records of discovering innovative treatments and targets in cancer, and the scientific team is executing multiple drug discovery strategies targeting the mechanisms that allow tumors to become resistant to current therapies.  The company is supported by investors with extensive experience in both drug development and the financing of life science companies and is located in South San Francisco, CA.

The qualified candidate will join a team focused on oncology target discovery and drug discovery efforts. In this position you will support these efforts by providing biology expertise and services including but not limited to the following:
•   Identification and functional assessment of therapeutic targets through RNAi and gene editing techniques
•   Analyze molecule’s mechanism of action utilizing flow cytometry, western, qPCR, proliferation and apoptosis assays, RNA-seq and other relevant assays
•   Execute biological assays (biochemical and cell-based)
•   Perform data analysis, reporting and integration with GraphPad Prism, Microsoft Office and other computer programs


•   BS or MS in biology, molecular biology, cell biology or related discipline with 2-3 years of experience is desirable.
•   Proficiency in cell culture and generation of stable cell lines through viral transduction, conditional gene knockdown/expression
•   Proficiency in DNA and RNA isolation, qPCR and other RNA analysis techniques
•   Experience with protein analysis: western, flow cytometry, immunofluorescence, ELISA
•   Experience with enzymatic assays and cell-based assays
•   Excellent computer skills combined with data analysis
•   Must be detail oriented, well organized, and have strong communication skills
•   Capable of fully understanding scope of projects and able to troubleshoot and identify solutions to arising issues
•   Excellent teamwork skills and the ability to work under the supervision of a senior member of the biology group, in a fast-paced, multi-disciplinary environment
•   Excellent work ethic, self-motivated, driven, dependable, hardworking