Research Associate/Senior Research Associate, Viral Vector Development and Production - Menlo Park, CA | Biospace
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Research Associate/Senior Research Associate, Viral Vector Development and Production

Adicet Bio, Inc.

Location:
Menlo Park, CA
Posted Date:
6/13/2017
Position Type:
Full time
Job Code:
Salary:
Required Education:
Bachelors Degree
Areas of Expertise Desired:
Assay, Biology, Biology Research, Cell Biology, Cell Culture, Flow Cytometry, Molecular Biology,

Job Description

Adicet Bio is seeking a highly motivated and experienced individual with a strong immunology and viral vector biology background to work on the development and clinical implementation of innovative immune cell therapies. The successful candidate will contribute to the advancement of Adicet’s proprietary immunotherapeutic cell engineering platform focused on genetic modification and expansion of human immune cells. Research Associates will primarily perform viral vector production and purification for pre-clinical evaluation and process scale-up activities.  Duties include management of source materials, reagents, cell banks, vector development lots and the production and analysis of engineered immune cell products under minimal supervision. Senior Research Associates will be expected to independently design and perform experiments, organize and analyze results.

Company
Adicet bio, Inc. is a privately held, preclinical stage biotechnology company that is engaged in the development of cutting-edge immunotherapies for cancer and other disease indications, with a focus on novel universal immune cell therapies. Adicet’s immune cell platform is complemented by expertise of its wholly owned subsidiary, Adicet Bio Israel Ltd., which identifies and validates novel disease specific peptide-MHC targets and generates T cell receptor-like antibodies that can be used to specifically target immune cells to diseased cells.
Adicet Bio was founded in late 2015 and closed a Series A financing of $51M in Jan 2016. This financing was led by OrbiMed and also included Novartis Venture Funds and Pontifax. In August 2016, Regeneron and Adicet Bio announced a strategic collaboration to discover and develop next-generation engineered immune-cell therapeutics, for which Adicet received a $25M upfront payment.
In September 2016, Adicet Bio was recognized and named by FierceBiotech to its “Fierce 15” Biotech Companies of 2016


Job Responsibilities (Include but not limited to)
•   Develop analytical methods to study and characterize engineered immune cell products
•   Assist in the development of standard operating procedures, analytical test methods, analytical sampling plans and batch records
•   Write, review and edit accurate technical documents
•   Work with a cross-functional team to advance development of immunotherapy products
•   Execute qualification in support of lead candidate selection, process development, product release and stability, and product characterization
•   Successfully execute and document laboratory procedures and experiments with great attention to detail
•   Other duties as assigned

Requirements

•   Bachelor or Master’s degree in Biological Sciences or related Biological (or relevant experience)
•   At least 2 years of experience in similar role in a laboratory with knowledge and experience in cell biology, cellular immunology, viral vector and molecular biology preferred.
•   This position requires experience with flow cytometry, cell based bioassays and ELISA or PCR techniques. Techniques in molecular biology, such as RT-PCR is a plus.
•   Hands on experience in primary cell culture, cell-based assays, biochemical assays or flow cytometry, viral vector production and transduction.
•   Use of perfusion and stirred tank bioreactors.
•   Use of large scale cell washing and formulation devices.
•   Experience with cell cryopreservation and other similar blood banking technologies
•   Ability to multitask and meet deadlines in a fast-paced environment
•   Ability to think critically and demonstrate troubleshooting and problem-solving skills
•   Excellent skills in Microsoft Office Suite and prior experience with statistical data analysis programs (JMP, Prism)
•   Strong organizational and record keeping skills.
•   Excellent interpersonal, verbal and written communication skills are essential in this collaborative work environment
•   Comfortable in a fast-paced small company environment with minimal direction and able to adjust workload based upon changing priorities
•   Self-motivated, detail-oriented, and willing to accept temporary responsibilities outside of initial job description.