Research Associate/ Senior Research Associate Pharmacology - San Diego, CA | Biospace
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Research Associate/ Senior Research Associate Pharmacology

Regulus Therapeutics, Inc.

San Diego, CA
Posted Date:
Position Type:
Full time
Job Code:
Required Education:
Bachelors Degree
Areas of Expertise Desired:

Job Description

Regulus Therapeutics Inc. (Nasdaq: RGLS) is a biopharmaceutical company located in San Diego, California leading the discovery and development of innovative medicines targeting microRNAs.

We are currently seeking an experienced Research Associate/ Senior Research Associate Pharmacology to join our team and advance our efforts in phenotypic screening for novel drug targets and compounds. For more information, visit

Position description and scope:

Regulus is seeking a highly motivated Research Associate to contribute to the identification and development of new microRNA targeted therapies.  The successful candidate will have extensive experience with in vivo models, as well as general knowledge on cellular and molecular biology. Industrial experience is required along with experience working in a matrix environment.  Required qualifications include hands-on experience with in vivo PK/PD and disease efficacy studies. All highly motivated applicants interested in exploring microRNA biology and function and developing novel therapeutics are encouraged to apply.  

Job responsibilities

1.   We are looking for strong experience in performing/developing various cell and molecular biology techniques including, cell culture (primary and stable cell lines), transfection, stable cell line generation, FACS analysis, MACS cell separation, ELISA, RNA purification, RT-qPCR, and other standard cell-based or biochemical assays, are required.

2.   In addition, good understanding of animal models for various therapeutic areas, and experience in performing in vivo pharmacology experiments including dosing of rodents (IV, SC, IP, PO) and harvesting/processing of tissue samples is expected.

3.   Basic understanding of oligonucleotides is preferred but not mandatory

4.   Experience in the kidney/liver disease space is desirable


Position Requirements:

•   BS/MS in Biology or related discipline
•   5-10 years hands on experience conducting in vivo pharmacology studies.
•   5 years of industrial experience is required.
•   Attention to detail, proficient reasoning skills in experimental design, data analysis, statistical methods and interpretation is a must.  
•   Excellent written and oral communication skills.
•   Familiarity and ease of use with GraphPad Prism, Microsoft Word, Excel, PowerPoint and Outlook
•   Independence, problem-solving abilities, self-motivation, resourcefulness and the ability to work in a fast paced team environment are essential.

Personal Competencies:

•   Effective interpersonal skills, including both written and oral communication skills
•   Highly organized, Strong analytical skills, highly attentive to details, and strong work ethic
•   Ability to work within schedules and deadline
•   Team player, intensely committed to success and getting the job done well in a highly dynamic environment
•   Ability to multitask, prioritize, and function in a fast-paced entrepreneurial environment
•   Self-motivated, ability to work independently while also willing to follow protocols
•   Willingness to rapidly learn new laboratory and data analysis methods
•   Demonstrated ability to generate reproducible results, and to teach others

Regulus Therapeutics Inc. (Nasdaq: RGLS) is a biopharmaceutical company leading the discovery and development of innovative medicines targeting microRNAs.  Regulus has leveraged its oligonucleotide drug discovery and development expertise to develop a well-balanced microRNA therapeutics pipeline complemented by a rich intellectual property estate to retain its leadership in the microRNA field.  Regulus is advancing several programs in renal, hepatic and central nervous systems diseases.
Regulus is located in La Jolla, California and is led by a seasoned executive team experienced in corporate management, business, science, drug discovery and development. Regulus' scientific advisory board consists of world-class scientists and some of the foremost authorities in the field of microRNA research.

Excellent salary and benefits package offered.

For immediate consideration, please click Apply Now above.

You can visit our website to find out more about our company and culture:

Reference job code: 544


Regulus Therapeutics, Inc, is proud to be an EEO Employer.