Research Associate/Senior Research Associate - Antibody Engineering - South San Francisco, CA | Biospace
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Research Associate/Senior Research Associate - Antibody Engineering

NGM Biopharmaceuticals, Inc.

South San Francisco, CA
Posted Date:
Position Type:
Full time
Job Code:
Required Education:
Bachelors Degree
Areas of Expertise Desired:
Antibody, Associate, Engineering, Research, Senior Research Associate,

Job Description

NGM Biopharmaceuticals, Inc. is a private biotech company dedicated to discovering and developing the next generation of medicines for the treatment of serious diseases.  Our experienced scientific team has joined forces with an impressive group of industry professionals, Nobel Laureates and other distinguished researchers to form a company where innovation and cutting edge science has provided the foundation for a robust drug discovery engine.  To date, NGM Bio has generated a pipeline of six drug candidates in various stages of development, including NGM282 that recently demonstrated proof-of-concept in a Phase 2 study in non-alcoholic steatohepatitis (NASH).  In 2015, we entered into a broad, strategic collaboration with Merck that will provide us with the resources and flexibility to pursue our ambitious R&D goals and further extend our pipeline of novel drug candidates.

We are currently looking for a highly motivated research associate/senior research associate to join our antibody engineering team that focuses on therapeutic antibody discovery and optimization using various molecular biology and protein engineering approaches. The person will mainly involve in the work of selecting and characterizing therapeutic antibodies from both naïve and immune sources, hybridoma sequencing, lead antibody humanization, developing cutting-age technologies for antibody discovery and optimization. The candidate is expected to work in a highly collaborative environment and to be able to work on multiple tasks simultaneously.


•   Conduct experiments on lead antibody selection, antibody humanization, murine antibody sequencing.
•   Isolate and characterize therapeutic antibodies from both naïve and immune sources.
•   Attend research project team meetings and present the results.
•   Stay abreast of latest scientific and technology advancements in the field


•   Having a wide range of molecular biology and antibody engineering techniques including RNA isolation, molecular cloning, sequencing analysis, mutagenesis, antibody library generation, screening and characterization.
•   Working experiences of hybridoma sequencing, phage and/or yeast display technologies will be a plus
•   Excellent team work and collaboration skills, being able to work in a cross-functional environment
•   Detail oriented with strong organizational and communication skills
•   Being able to work in a fast paced, changing environment with demonstrated ability to manage multiple tasks with a high degree of self-motivation.


•   BA/BS in biology/biotechnology-related discipline with over 2-3 years or MS degree with 1-2 years of laboratory experience.

NGM offers a creative, collaborative, and highly challenging scientific environment, along with a strong compensation package that includes salary, stock options, 401(k) and a comprehensive benefits package.