Research Associate: Protein Engineering - La Jolla, CA | Biospace
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Research Associate: Protein Engineering

California Institute for Biomedical Research

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Location:
La Jolla, CA
Posted Date:
11/28/2016
Position Type:
Full time
Job Code:
105
Salary:
Required Education:
Bachelors Degree
Areas of Expertise Desired:
Associate, Engineering, Protein, Research,

Job Description



The California Institute for Biomedical Research is seeking a talented and experienced individual to fill a Research Associate position in the field of Immuno-Oncology. The candidate will work as part of an interdisciplinary team to develop novel protein therapeutics for the CAR-T cell platform and bispecific antibody program. Research activities will focus on molecular biology and protein biochemistry. An ideal candidate would possess the following skills:
•   A strong background in molecular biology is essential. The candidate must have experience with classical and assembly-based cloning methods. Proficiency with DNA/RNA isolation and purification, site-directed mutagenesis, and PCR is required. Experience in genome engineering and phage display is a plus.
•   Experience with transient mammalian expression systems (HEK and/or CHO) and bacterial expression is essential. Prior experience in antibody, Fab, and/or scFv expression is highly preferred.
•   Experience with purification of intracellularly expressed and secreted proteins, column-based chromatography (e.g., affinity capture, IEX, SEC, HIC), and SDS-PAGE is essential.
•   Experience with protein mass spectrometry, qualitative and quantitative analysis by HPLC, and protein-protein binding kinetics is a plus.
•   The candidate must have excellent oral and written communication skills and a strong work ethic.
•   Excellent ability to research, conceptualize, and organize project designs and maintain detailed documentation
•   Highly motivated, creative, and devoted to project goals
•   Able to collaborate proficiently and communicate effectively with colleagues and management teams
•   Able to contribute in a meaningful way to scientific discourse

Requirements


•   BA/BS, MS, or PhD in biology, molecular biology, biochemistry or related area
•   3-5 years' of experience in protein science, molecular biology, or related setting
PHYSICAL REQUIREMENTS
Details of established essential functions for this position will be addressed/discussed during the interview process.