Research Associate II (NCI) - Frederick, MD | Biospace
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Research Associate II (NCI)

Leidos Biomedical Research, Inc.

Frederick, MD
Posted Date:
Position Type:
Full time
Job Code:
Required Education:
Bachelors Degree
Areas of Expertise Desired:

Job Description

Leidos Biomedical Research, Inc. (LBRI), a wholly owned subsidiary of Leidos, operates the Frederick National Laboratory for Cancer Research (FNLCR). FNLCR is a Federally Funded Research and Development Center (FFRDC) sponsored by the National Cancer Institute (NCI). It is the only FFRDC dedicated to biomedical research. Through its status as an FFRDC, FNLCR provides NCI and others with a unique national resource to accelerate the development and delivery of effective preventive, diagnostic, and therapeutic products for cancer and AIDS.

The breadth of FNLCR’s activities spans the research and development spectrum, including investigator-initiated, hypothesis-driven research into cancer and AIDS; advanced technology programs focused on genetics and genomics, proteins and proteomics, imaging, nanotechnology, bioinformatics, and laboratory animal sciences; clinical operations in support of NCI and National Institute of Allergy and Infectious Diseases (NIAID)-sponsored clinical trials, as well as NCI drug discovery and development efforts; and management and operations of biopharmaceutical development and manufacturing programs under current Good Manufacturing Practice conditions for NCI and NIAID. Administrative, procurement, financial, safety, and facilities support is provided to these R&D activities through state-of-the-art business processes.  LBRI has approximately 1,900 employees and manages an annual operating budget of approximately $450M.

For more information about Leidos Biomedical Research Inc., please visit our webpage at

The Strategic Pilots Incubator (SPI) is responsible for the development and management of a portfolio of exploratory projects that are inherently multidisciplinary that impact cancer research and treatment. Projects aim to analyze the complex interactions in tumor cells and tissues and model systems, blending the best of new physics and engineering based advances with established technologies enabling new opportunities for deeper understanding of tumor biology and cancer progression.  Using the latest tools in understanding human performance under stressful conditions can be used to understand and hopefully mitigate the toxic effects of cancer therapy for the patient.

We are recruiting for a Research Associate II (RAII) to support a newly established High Content Pathology Facility at the Frederick National Laboratory for Cancer Research. The new facility will revolve around analysis of tissue and circulating tumor cells.  We are looking for a motivated individual interested in acquiring new skills in a cutting-edge and developing technology who has the ability to function independently and as a team member in a specialized research laboratory.
The Research Associate II will be responsible for: 1) processing and preparation of human blood and tissue samples, 2) preparing and optimizing antibody-metal conjugates for use in multiplex assays,  3) staining of cells and tissue sections using immunocytochemistry (ICC) and immunohistochemistry (IHC) techniques, 4) establishing and following standardized operating procedures (SOP), 5) performing quality control testing on instruments, 6)maintaining records and laboratory environment, and 7) maintaining laboratory equipment as needed.


Possession of a Bachelor's degree from an accredited college/university according to the Council for Higher Education Accreditation (CHEA) in a field related to biomedical research or four (4) years equivalent experience in the appropriate field in lieu of degree.
Foreign degrees must be evaluated for U.S. equivalency.
Two (2) years related biomedical experience
Experience with ICC and IHC techniques
Proven capability of using various analytical instruments for characterization
Ability to maintain precise, accurate records
Ability to develop/optimize new assays under the direction of a lab supervisor
Ability to pick up new technologies quickly and ultimately troubleshoot
Working knowledge of Microsoft Office
Experience with microscopy instrumentation, data acquisition, and interpretation
Experience with tissue and blood sample handling
Familiarity with Flow Cytometry and/or Mass Cytometry instrumentation
Familiar with usage of a Laboratory Information Management System (LIMS)