Research Associate II – Genomics/NGS (NCI) - Frederick, MD | Biospace
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Research Associate II – Genomics/NGS (NCI)

Leidos Biomedical Research, Inc.

Frederick, MD
Posted Date:
Position Type:
Full time
Job Code:
Required Education:
Bachelors Degree
Areas of Expertise Desired:

Job Description

The Molecular Characterization Laboratory (MoCha) is part of Leidos Biomedical Research’s Clinical Research Directorate (CRD) at the Frederick National Laboratory for Cancer Research. The MoCha Laboratory is responsible for providing high-level research in support of the NCI-Cancer Diagnostics Program (CDP) within the Division of Cancer Treatment and Diagnosis (DCTD). MoCha is charged with the development and application of genomic assays for use in medical research and diagnostics for DCTD-sponsored national extramural clinical trials.

The Research Associate II will be working in cutting edge genomic research using next generation sequencing (NGS) and other genomic assays to support DCTD projects e.g., Patient Derived Xenograft Models (PDM) project, genomic characterization of patient samples enrolled in clinical trials.

Performs genomics research and/or assay development in collaboration with others for projects
Makes detailed observations, analyzes data and interprets results
Investigates, creates and develops new methods and technologies for project advancement
Maintains a high level of professional expertise through familiarity with scientific literature
May participate in scientific conferences and contribute to scientific journals
May be responsible for identifying patentable inventions
May act as principal investigator in conducting own experiments
Exercises independent judgment in developing and/or modifying methods and techniques for solving scientific problems
Performs molecular assays by adherence to SOPs
Develops new assays and applies the methods/assays utilizing sound scientific judgement
Writes SOPs and performs formal reporting of research data, including presentations and/or scientific publications
Maintains knowledge of the most recent literature and scientific presentations relevant to projects
Maintains essential laboratory supplies and monitors equipment for optimum performance


To be considered for this position, you must minimally meet the knowledge, skills, and abilities listed below:
Possession of a Bachelor's degree in a related field from an accredited college/university according to the Council for Higher Education Accreditation (CHEA) in a field related to biomedical research/scientific discipline (Additional qualifying experience may be substituted for the required education).
Foreign degrees must be evaluated for U.S. equivalency
A minimum of five (5) years of experience
Strong technical skills in molecular biological and genomic assays
Ability to independently evaluate the suitability and quality control of research or production assays or tests, develop and follow SOPs, and analyze and report data
Ability to track information in a large cohort of samples and monitor progress of multiple projects
Adequate computer skills to document, organize, and present experimental data
Strong critical thinking and problem solving skills
Ability to communicate effectively, both verbally and in writing
Must be able to obtain and maintain a Security Clearance
Candidates with these desired skills will be given preferential consideration:
Experience in NGS genomic profiling assays (i.e. whole exome sequencing and RNA sequencing), digital PCR, nanostring, microarray
Experience in genomic assay development and workflow automation
Familiarity with clinical oncology studies and other protocol-driven clinical research