Research Associate I/II, Cell Biology, Translational Research - Bothell, WA | Biospace
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Research Associate I/II, Cell Biology, Translational Research

Seattle Genetics, Inc.

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Location:
Bothell, WA
Posted Date:
9/18/2017
Position Type:
Full time
Job Code:
2001
Salary:
Required Education:
Bachelors Degree
Areas of Expertise Desired:

Job Description

Summary:

We are seeking a highly motivated Research Associate with a strong cell biology background to join the Translational Research group at Seattle Genetics, an established leader in the development of tumor-directed antibody-drug conjugates (ADCs).   The primary responsibilities will be to conduct innovative research aimed at advancing novel therapeutics into our drug development pipeline as well as furthering our understanding of drug mechanism(s) of action in cancer model systems. The successful applicant will have demonstrated competency in cell and cancer biology methodologies and be able to independently design, conduct, troubleshoot, and interpret experiments.

Responsibilities:

   
        
  • Contribute intellectually and experimentally to the discovery and validation of potential new oncology drug candidates
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  • Execute molecular and cell-based methodologies including multicolor flow cytometry, immunofluorescent and live cell microscopy, cytotoxicity assays, ELISA, qPCR, western blotting, and co-immunoprecipitation
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  • Manipulation of primary cells and cancer cell lines, including standard cell culture, co-culture assays, viral transduction, CRISPR/Cas9 and transfection
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  • Develop novel cancer biology assays that more accurately mimic the disease setting as well as provide tools to further understand the mechanism of our novel therapeutics
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  • Communicate experimental findings in written and oral format to internal groups as well as cross-functional teams
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Requirements

Qualifications:

  • B.A./B.S. or M.A./M.S. in a relevant field with 2+ years of experience in an academic or biotech research setting
  • Working knowledge of cell biology or biochemistry in the context of either cancer or immunology
  • Ability to work both independently and as part of a team in a fast paced dynamic environment
  • Exceptional trouble-shooting and communication skills
  • Ability to utilize data analysis tools such as Excel, Powerpoint, Spotfire, and GraphPad Prism for both experimental documentation and presentations
  • Experience elucidating mechanisms of cellular response such as signal transduction, cell-cell communication, or transcriptional activation/repression
  • Experience with high throughput methods is a plus, particularly high content imaging
  • Excellent organizational, presentation, and interpersonal skills

Seattle Genetics is an equal opportunity employer. All qualified applications will receive consideration for employment without regard to race, color, religion, sex, national origin, protected veteran status, or disability status.

To apply for this position, please visit www.seattlegenetics.com/careers