Research Associate - La Jolla, CA | Biospace
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Research Associate

Cellular Approaches, Inc.

La Jolla, CA
Posted Date:
Position Type:
Full time
Job Code:
Required Education:
Bachelors Degree
Areas of Expertise Desired:
Associate, Research,

Job Description


Cellular Approaches is a biotechnology company focused on harnessing patients’ innate immune systems to treat myriad diseases. Building on recent innovations in cellular biology to create novel cell-based therapeutics, the company focuses on extending lives through treatments for infectious diseases, neuro-degenerative diseases, and aging. Cellular Approaches is developing a first-in-class, innate-immunity pipeline of therapeutics. The company plans to initiate its first clinical trials in 2018.

The company is funded and being incubated by two of the leading venture capital firms in the San Diego Area. Working predominantly in a “stealth” capacity, the company is rapidly growing in San Diego as well as through a network of development partnerships around the country.  The company is located in the Torrey Pines area of San Diego, California.  

Summary / Overall Purpose

Under the direction of senior staff, we seek a research associate to perform duties related to the isolation, differentiation, and characterization of macrophages from humans and rodents per established protocols.  Specific duties may include isolation and culturing of monocytes from human blood and rodent blood / bone marrow, biochemical assays (ELISA, qPCR), immunofluorescence microscopy and flow cytometry.  May also be involved in some aspects of assay development and establishing standard operating procedures (SOPs).    

Essential/Primary Duties, Functions and Responsibilities

•   Under direction of senior staff, executes a battery of assay technologies with established protocols to characterize monocytes / macrophages, including ELISA, qPCR, flow cytometry, immunofluorescence microscopy and in vitro killing assays.
•   May participate in new assay development
•   Primary immune cell isolation and cell culture with meticulous aseptic technique
•   Prepares detailed protocols (SOPs) that enable transfer of techniques
•   Detailed recordkeeping of experimental steps and results
•   Reporting of results to supervisor and internally at group meetings
•   Other duties as assigned, including the management of laboratory equipment and supplies and interfacing with vendors.


Work Experience:

•   Minimum 1 year research experience in an academic or industrial laboratory setting, industry experience strongly preferred

Functional/Technical Knowledge and Skills

•   Previous experience in some of the following:  primary human mammalian immune cell isolation and culture, ELISA, qPCR, flow cytometry, immunofluorescence microscopy
•   Previous experience in macrophage cell culture and characterization a plus


•   B. A. or B.S. in immunology, biology, physiology, molecular and cellular biology, or closely related field


•   Work collaboratively with multi-disciplinary groups in a fast-paced work environment
•   Able to work independently on established protocols / SOPs following training
•   Excellent verbal and written communication skills and track record of ability to effectively present scientific data
•   Detail oriented; proven track record of detailed, reproducible protocol generation that can be broadly reproduced
•   Positive attitude
•   Keeps calm under pressure
•   Some weekend work will be required