PACT Pharma is an exciting new company with laboratories in Hayward, CA and Pasadena, CA. PACT was created to develop adoptive T-cell therapies for the treatment of cancer. PACT utilizes technology licensed from the laboratories of Drs. Heath and Baltimore (Caltech) to identify T cells that recognize mutations that are specific to each patient’s cancer. The unique T-cell receptor (TCR) sequences obtained from these neoantigen-reactive cells are then expressed on T cells from the patient’s own blood to produce PACT’s therapeutic product: an army of fresh, active T cells that, following infusion into the patient, recognize and attack each patient’s unique cancer cells.
We are currently seeking a Research Associate in biochemistry. This full-time opportunity will be for one year with the possibility to be extended. The following position is located in Pasadena, CA.
Research Associate - Biochemistry
You will express, purify, fold, and label proteins using standard bacterial expression systems, fast protein chromatography systems, and then to perform cellular and biomolecular assays using those proteins. In some cases, the associated will be expected to work with vendors to obtain specific proteins, and to validate the quality of those proteins. The associate is expected to carry out routine care and maintenance of the associated protein chromatography and assay equipment. Experience in protein expression (e coli) and purification, FPLC, standard biological assays (Western Blots, ELISAs) preferred.
Duties for position include:
• Working with vendors to obtain reagents in a timely manner, and working to validate those reagents
• Working within a team of researchers to prepare reagents for the analysis of patient cells, and collaborating on that analysis
• Develop specific protocols and SOPs for chemical or biomolecular reagent production, as appropriate, according to Company Guidelines
• Routine maintenance of specific equipment and facilities
Position requires: B.Sc./M.Sc. in Cell Biology or Bio-chemical Engineering or a related field, or equivalent technical training with a minimum of 2 years of post-graduate experience in a closely related field.