Process Development Engineer/Senior Process Development Engineer/Senior Research Associate/Associate - Menlo Park, CA | Biospace
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Process Development Engineer/Senior Process Development Engineer/Senior Research Associate/Associate

Adicet Bio, Inc.

Location:
Menlo Park, CA
Posted Date:
4/10/2017
Position Type:
Full time
Job Code:
Salary:
Required Education:
Bachelors Degree
Areas of Expertise Desired:
Cell Culture, Process Development, Process Engineer, Research Scientist, Senior Research Associate,

Job Description

Company:
Adicet bio, Inc. is a privately held, preclinical stage biotechnology company that is engaged in the development of cutting-edge immunotherapies for cancer and other disease indications, with a focus on novel universal immune cell therapies. Adicet’s immune cell platform is complemented by expertise of its wholly owned subsidiary, Adicet Bio Israel Ltd., which identifies and validates novel disease specific peptide-MHC targets and generates T cell receptor-like antibodies that can be used to specifically target immune cells to diseased cells.
Adicet Bio was founded in late 2015 and closed a Series A financing of $51M in Jan 2016. This financing was led by OrbiMed and also included Novartis Venture Funds and Pontifax. In August 2016, Regeneron and Adicet Bio announced a strategic collaboration to discover and develop next-generation engineered immune-cell therapeutics, for which Adicet received a $25M upfront payment.
In September 2016, Adicet Bio was recognized and named by FierceBiotech to its “Fierce 15” Biotech Companies of 2016

Responsibilities:
AdicetBio is seeking a highly motivated and experienced individual with a strong cell culture/upstream development background and experience in bioreactor and media development. The successful candidate will contribute to the development of Adicet’s proprietary immunotherapeutic manufacturing platform. The candidate will be responsible for small scale optimization, scale up of manufacturing process, and process characterization and validation from pre-clinical to clinical manufacturing. The candidate will also support and contribute to regulatory submission and technology transfer.

Requirements

•   BS/MS in chemical engineering/biological sciences or a related field
•   Minimum of 2 years (Process Development Engineer/ Associate) / 5 years (Sr. Process Development Engineer/ SRA) experience in cell culture process development
•   Experienced in bioreactor unit operations including modeling, scale up/scale down, process characterization and validation
•   Experienced in cell culture media development
•   Experienced in process and technology transfer
•   Preferred but not required: experience with handling of human primary cells, biological specimens, particularly blood, isolation of PBMC using density gradient centrifugation (Ficolling). Separation of B, T and NK cells by cell enrichment and depletion using magnetic beads, or sorting
•   Cell culture media development and primary cell hands on experience development is a plus
•   Ability to multitask and meet deadlines in a fast-paced environment
•   Highly motivated, organized and disciplined record keeping
•   Exceptional verbal and written communication skills