Principal Scientist - Translational Medicine - Gaithersburg, MD | Biospace
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Principal Scientist - Translational Medicine

MedImmune, LLC

Gaithersburg, MD
Posted Date:
Position Type:
Full time
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Job Description

                                       Location:Gaithersburg, Maryland, United States
Job reference: R-000945

Posted date: Jan. 26, 2017



   Principal Scientist – Translational Medicine  

   If you’re inspired by the possibilities of science to change lives and you thrive when making brave decisions – join us.  

   MedImmune is the worldwide biologics research and development arm of AstraZeneca. Here, you’ll have the opportunity to make a difference in people’s lives every day. As one of the world’s premier biotechnology companies, our mission is centered on delivering life-changing products that advance world health, and help fight and cure disease.  As a Principal Scientist, Translational Medicine in Gaithersburg, MD you’ll play a pivotal role in channelling our scientific capabilities to make a positive impact on changing patients’ lives.  

   We’re constantly pushing the boundaries of science to deliver life-changing medicines to patients, with a passion for discovery and a pipeline to show for it. We’re pioneering innovative research and exploring novel pathways across key therapeutic areas including oncology, respiratory, inflammation and autoimmunity, cardiovascular and metabolic disease, and infection and vaccines. And we’re industry-leading in immunology, protein engineering and translational science. We offer a unique and strong collaborative network as part of the AstraZeneca family, as together we explore synergies between small and large molecules.  


    MedImmune has a dynamic environment that fosters collaboration and innovation. We attract top minds, and we nurture and build top talent  

   Main Duties and Responsibilities  


   We are seeking a dynamic leader in translational medicine.  As a Principal Scientist, you will provide exceptional scientific and strategic leadership to understand molecular heterogeneity of human respiratory diseases and apply this knowledge to aid development of MedImmune’s exciting portfolio for asthma and COPD.  

   You will help to lead a team of lab-enabled scientists / Sr. scientists and bioinformatics analysts to mine genomic and proteomic data from internal and external collaborations and clinical trials to develop high profile manuscripts and help establish scientific leadership for MedImmune.  In addition, you  will lead one or more Translational Science sub-teams that will apply knowledge derived from such analysis to develop testable personalized healthcare strategies.  In this role, you will also have the opportunity to lead diagnostic teams to turn predictive biomarkers into companion diagnostics.  

   This is an important, high profile and visible role where you can leverage your outstanding communication and leadership skills, to build strong relationships with key stakeholders in Clinical, Research and other relevant functions within MedImmune and external academic collaborators. You should be viewed as a strong scientific and strategic leader who can work with a fast-paced clinical and product development organization to translate fundamental insights into the molecular heterogeneity of human disease into targeted therapeutic and biomarker hypotheses that can be tested in clinical trials.   You will be expected to drive the publication of biomarker data in top-tier scientific, technical or medical journals.  


   Essential Requirements  

  •      MD, MD/PhD or PhD degree in a relevant scientific field (e.g. molecular biology, cell signaling, bioinformatics) or equivalent experience    
  •      Minimum of 10 years post-MD/PhD experience in an academic and/or industry setting    
  •      Outstanding record of innovative contributions to translational sciences in respiratory as evidenced by a strong publication record including first / senior-authored publications in top-tier journals, inventorship on patents/filings and presentations at important conferences.    
  •      At least 8-10 years of prior experience managing a group of research associates, scientists or leading a matrix team    
  •      Outstanding verbal and written communications skills are a must.    

   Desirable Requirements  

  •      Experience in analyzing large datasets including genomic and proteomic  together with a sound understanding of critical development functions, e.g. Clinical Sciences, Biomarker Development, Translational Medicine    

   Next Steps – Apply today!  


   To be considered for this exciting opportunity, please complete the full application on our website at your earliest convenience – it is the only way that our Recruiter and Hiring Manager can know that you feel well qualified for this opportunity.  If you know someone who would be a great fit, please share this posting with them.  

   AstraZeneca is an equal opportunity employer. AstraZeneca will consider all qualified applicants for employment without discrimination on grounds of disability, sex or sexual orientation, pregnancy or maternity leave status, race or national or ethnic origin, age, religion or belief, gender identity or re-assignment, marital or civil partnership status, protected veteran status (if applicable) or any other characteristic protected by law.