If you’re inspired by the possibilities of science to change lives and you thrive when making brave decisions – join us.
MedImmune is the worldwide biologics research and development arm of AstraZeneca. Here, you’ll have the opportunity to make a difference in people’s lives every day. As one of the world’s premier biotechnology companies, our mission is centered on delivering life-changing products that advance world health, and help fight and cure disease. As a Principal Scientist in Gaithersburg, MD, you’ll play a pivotal role in channeling our scientific capabilities to make a positive impact on changing patients’ lives.
We’re constantly pushing the boundaries of science to deliver life-changing medicines to patients, with a passion for discovery and a pipeline to show for it. We’re pioneering innovative research and exploring novel pathways across key therapeutic areas including oncology, respiratory, inflammation and autoimmunity, cardiovascular and metabolic disease, and infection and vaccines. And we’re industry-leading in immunology, protein engineering and translational science. We offer a unique and strong collaborative network as part of the AstraZeneca family, as together we explore synergies between small and large molecules.
MedImmune has a dynamic environment that fosters collaboration and innovation. We attract top minds, and we nurture and build top talent.
Main Duties and Responsibilities
Those who join MedImmune feel a sense of ownership about their future. They thrive with a recognized leader in the biotechnology industry and the wholly-owned subsidiary of AstraZeneca plc. Here, you will join passionate professionals who advance science, technology and medicine to develop products designed to help people live better lives. You will excel in an environment characterized by respect, integrity and growth opportunities... that encourages both individual contribution and collaborative entrepreneurial thinking. Our products and/or product candidates are designed to address areas of need in cardiovascular / metabolic disease (CVMD) and neuroscience. Explore a MedImmune career as we strive to better more lives, more often, around the world.
We are seeking a highly motivated individual to support large molecule (peptide, antibody, and therapeutic protein), preclinical drug discovery efforts in the Department of Cardiovascular / Metabolic Diseases for the treatment of obesity, type 2 diabetes (T2D) and its complications (chronic kidney disease (CKD), heart failure and nonalcoholic steatohepatitis (NASH)). The major responsibilities of this position involves: 1) leading a team of scientists in progressing a growing preclinical drug discovery pipeline ranging from project start to initiation of GLP toxicology studies; 2) contributing to an assessment of external business alliances and in-licensing opportunities; 3) develop novel strategies to screen and identify new drug targets, and 4) to instill scientific innovation through personal leadership and mentorship.
The ideal candidate must have expert knowledge in Metabolic Regulation and Metabolic Disorders as evidenced by an excellent record of publications in peer-reviewed journals with high-impact, proven track-record with preclinical drug discovery (preferably biologics) from conception of project to early clinical trials with excellent management skills. The person in this role should have the ability to set high but reachable goals, define priorities, manage individual performance, and infuse the team with a sense of purpose and direction, scientific creativity, as well as influence scientific thinking and direction of multifunctional drug discovery projects. They should also be able to build and manage collaborations within and outside the organization, be well organized with outstanding interpersonal and oral/written communication skills, and be able to manage several projects at a time.
- Expert scientific knowledge of T2D, obesity, CKD, heart failure and/or NASH.
- Conducts, plans and leads one or more highly complex scientific projects, including determining objectives, organizing activities and strategic direction.
- An emerging leader as evidenced by internal consulting, mentoring and project team membership and active support.
- Maintains high level of expertise through review of current scientific literature, submissions to scientific journals, and attendance and participation at conferences focused on the research and development efforts of the company.
- Decisions or recommendations consistently result in achievement of significant project objectives.
- Through collaboration with management, expands business opportunities for the company and development opportunities for scientists.
PhD (11-13 yr) MS (15-17 yr) or BS (17-20 yr), in biology/biochemistry with a specialization in Metabolic Disorders.
- Experience in pharmaceutical/biopharmaceutical industries and excellent publication record.
- Outstanding team leadership skills.
Next Steps – Apply today!
To be considered for this exciting opportunity, please complete the full application on our website at your earliest convenience – it is the only way that our Recruiter and Hiring Manager can know that you feel well qualified for this opportunity. If you know someone who would be a great fit, please share this posting with them.
AstraZeneca is an equal opportunity employer. AstraZeneca will consider all qualified applicants for employment without discrimination on grounds of disability, sex or sexual orientation, pregnancy or maternity leave status, race or national or ethnic origin, age, religion or belief, gender identity or re-assignment, marital or civil partnership status, protected veteran status (if applicable) or any other characteristic protected by law.