Pathologist (NCI) - Frederick, MD | Biospace
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Pathologist (NCI)

Leidos Biomedical Research, Inc.

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Location:
Frederick, MD
Posted Date:
8/8/2017
Position Type:
Full time
Job Code:
639338
Salary:
Required Education:
Medical Doctor
Areas of Expertise Desired:
Pathology,

Job Description

PROGRAM DESCRIPTION
The Molecular Characterization Laboratory (MoCha) is part of Leidos Biomedical Research’s Clinical Research Directorate (CRD) at the Frederick National Laboratory for Cancer Research. The MoCha Laboratory is responsible for providing high-level research in support of the NCI-Cancer Diagnostics Program (CDP) within the Division of Cancer Treatment and Diagnosis (DCTD). MoCha is charged with the development and application of genomic assays for use in medical research and diagnostics for DCTD-sponsored national extramural clinical trials.

KEY ROLES/RESPONSIBILITIES
The Pathologist will:
Support DCTD in their initiative to establish the creation of cutting edge genomic assays used for molecular profiling of patient specimens
Assist the MoCha CLIA Director in the review of next generation sequencing (NGS) clinical trial results and sign-off on patient reports; current efforts utilize NGS and gene expression profiling from formalin fixed paraffin embedded specimens
Represent laboratory activities as part of regulatory meetings
Independently perform clinical duties and function as a collaborator with the Principal Investigators (PI) Oncologists
Interact with assay development groups and contribute to efforts to keep technologies current and effective
Provide medical oversight of clinical evaluations necessary to conduct clinical laboratory studies in support of DCTD/Cancer Therapy Evaluation Program (CTEP) sponsored trials
Have direct involvement in histological interpretation of patient derived xenograft models for an ongoing project under DTCD
Author document, review pertinent research and clinical protocols
Contribute to the development and refinement of protocol approaches and methods
This position will be located in Frederick, Maryland.

Requirements

Basic Qualifications:
To be considered for this position, you must minimally meet the knowledge, skills, and abilities listed below:

This is a dual level requisition. It may be filled at either a Physician II or Physician III level.

Basic Qualifications for a Physician II:
Current professional license in Medicine in a state, Territory, or Commonwealth of the United States, or in the District of Columbia
Will be required to obtain State of Maryland medical license once offer is accepted
Completion of medical residency and/or fellowship in applicable specialty area
Board certified in applicable specialty area or equivalent clinical experience
A minimum of one (1) year of relevant experience
Basic Qualifications for a Physician III:
Current professional license in Medicine in a state, Territory, or Commonwealth of the United States, or in the District of Columbia
Will be required to obtain State of Maryland medical license once offer is accepted
Completion of medical residency and/or fellowship in applicable specialty area
Board certified in applicable specialty area or equivalent clinical experience
A minimum of three (3) years of relevant experience
Both the Physician II and Physician II require:
Training/experience in the field of oncology and/or pathology
In depth understanding of quality metrics data for NGS platforms
Experience reviewing results of germline and/or somatic NGS assays for validity
Experience Interpreting variants in the context of the medical literature (experience with oncology and germline diagnostics including hereditary cancer syndromes)
Experience corresponding with medical geneticists and oncologists on interpretation of results
Professional mastery of clinical research concepts and processes
Knowledge/experience of molecular assays
Expertise in clinical research protocol implementation and management
Ability to perform genomic analysis using NGS tools
Ability to successfully perform in a highly matrix collaborative team
Proven track record of relevant publications
Background with federally-regulated research grants, clinical trials or pharmaceutical projects
Working knowledge of Good Laboratory Practices (GLP) and CMS CLIA regulations (or equivalent regulatory programs, e.g. CAP)
Strong writing skills and ability to author documents including manuscripts for publications, SOPs, clinical protocols, etc.
This position is subject to obtaining a Security Clearance
Preferred Qualifications:
Candidates with these desired skills will be given preferential consideration:
Supervisory experience
Regulatory knowledge pertinent to CLIA or FDA guidelines for clinical assays
Familiarity with patient derived xenograft and pre-clinical drug studies
Excellent communication skills (written and oral)
Ability to work effectively in a team-oriented environment
Ability to identify and solve complex problems
Strong organizational and multitasking skills