Manufacturing Scientist - Downstream - Austin, TX | Biospace
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Manufacturing Scientist - Downstream

Molecular Templates

Austin, TX
Posted Date:
Position Type:
Full time
Job Code:
Required Education:
Masters Degree
Areas of Expertise Desired:

Job Description

Company Description:
Molecular Templates (MTEM) is a clinical stage biopharmaceutical company focused on the development of a next generation immunotoxin platform technology called Engineered Toxin Bodies (ETB) in oncology. MTEM’s lead program, MT-3724, is in clinical development for non-Hodgkin’s lymphoma and additional pipeline drug candidates are being advanced toward clinical development for a variety of cancers. For more information, please visit MTEM’s website at

Position Overview:
The Manufacturing Scientist will primarily conduct downstream processing for manufacturing activities. The position entails day-to-day management of operations related to protein purification and other manufacturing activities; process improvement; protocol development and execution; batch record creation and completion; data analysis; adherence to laboratory and company policies; assisting in training and productivity oversight of manufacturing associates or technicians as needed. This position will require excellent technical, analytical and problem-solving skills, along with ability to operate independently on progressively more complex activities and projects.

Job Responsibilities will include:
•   Perform protein purification while working independently and consulting with leadership on design and execution. This includes but not limited to: buffer and solution preparation, various filtration methods, centrifugation, chromatography, column packing and packed bed qualification, various sterilization methods, vialing and labeling; maintaining knowledge of scientific trends and industry processes through readings, conferences and seminars; reviewing literature to enhance or improve manufacturing procedures and methods.
•   Conduct protein characterization using common laboratory techniques such as SDS-PAGE and SE-HPLC.
•   Maintain required documentation in an accurate and timely manner, and adhere to written procedures, including manufacturing batch records.
•   General laboratory duties include: order lab supplies, maintain inventory and reagents, analysis of manufacturing data and presentation of summary results to team, monitoring production trends and identifying potential issues or opportunities for improvement, proper maintenance of laboratory equipment.
•   Implement complex projects and process development, as needed.

Reporting Structure:
This position has no direct reports but may provide direction and guidance on day-to-day work and may have a lead role. This position reports to the Executive Vice President of Manufacturing.

Molecular Templates, Inc. is an Equal Opportunity Employer and offers competitive salaries and benefits.


•   Master’s degree or higher in Applied or Life Science
•   Minimum of 3 years of relevant experience in laboratory setting, preferably conducting or supporting protein purification
•   Excellent problem solving and analytical skills
•   Excellent project management, time management and multi-tasking skills
•   Excellent written and verbal communication skills
•   Excellent computer skills
•   Ability to function independently and exercise good judgement
•   Ability to identify problems and solutions then take action to resolve