Director/Associate Director, Translational Science Lead for Cardiovascular Metabolic Diseases - South San Francisco, CA | Biospace
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Director/Associate Director, Translational Science Lead for Cardiovascular Metabolic Diseases

NGM Biopharmaceuticals, Inc.

South San Francisco, CA
Posted Date:
Position Type:
Full time
Job Code:
Required Education:
Areas of Expertise Desired:
Associate, Cardiovascular, Director, Translational,

Job Description


NGM Biopharmaceuticals, Inc. is a private biotech company dedicated to discovering and developing the next generation of medicines for the treatment of serious diseases.  Our experienced scientific team has joined forces with an impressive group of industry professionals, Nobel Laureates and other distinguished researchers to form a company where innovation and cutting-edge science has provided the foundation for a robust drug discovery engine.  To date, NGM Bio has generated a pipeline of six drug candidates in various stages of development, including NGM282 that recently demonstrated proof-of-concept in a Phase 2 study in non-alcoholic steatohepatitis (NASH). We have many more in preclinical development. In 2015, we entered into a broad, strategic collaboration with Merck that will provide us with the resources and flexibility to pursue our ambitious R&D goals and further extend our pipeline of novel drug candidates.  

We are recruiting a motivated scientist, at the Research Associate or Senior Research Associate level, to join our Protein Sciences group.


•   A member of Translation Science leadership team, and responsible for the translational strategies for the programs in cardiovascular & metabolic disease area.
•   Understand target and pathway biology to facilitate the selection of candidate drugs and their clinical applications
•   Develop, validate and execute clinical biomarker assays in house, and transfer assays to CRO labs as needed, including a portion of hands-on bench works
•   Understand GLP/GCP requirements, and ensure data quality, integrity and timeliness
•   Biomarker data analysis and interpretation, and their relationship to drug exposure, efficacy and safety
•   Presentations and publications for internal and external communications



•   PhD degree in Biology or a related field, with at least 12 years of relevant experience in CVMD
•   Strong record of scientific accomplishments in both research and development phases of drug development
•   Productive experience with forming biomarker hypotheses and their testing
•   Successful in carrying out assay development, validation, and execution for clinical studies, including sample tracking, testing, and data collection from CRO labs
•   Proficient in biomarker data analysis and how it may impact the drug development process
•   Experience with metabolomics and lipidomics is desirable

NGM offers a creative, collaborative, highly challenging scientific environment, along with a strong compensation package that includes salary, stock options, 401(k) and a comprehensive benefits package.