Clinical Pharmacokineticist - Gaithersburg, MD | Biospace
Get Our FREE Industry eNewsletter

Clinical Pharmacokineticist

MedImmune, LLC

Gaithersburg, MD
Posted Date:
Position Type:
Full time
Job Code:
Required Education:
Areas of Expertise Desired:

Job Description

Gaithersburg, Maryland, United States
Job reference: R-007271
Posted date: May. 15, 2017

If you’re inspired by the possibilities of science to change lives and you thrive when making brave decisions – join us.

MedImmune is the worldwide biologics research and development arm of AstraZeneca. Here, you’ll have the opportunity to make a difference in people’s lives every day. As one of the world’s premier biotechnology companies, our mission is centered on delivering life-changing products that advance world health, and help fight and cure disease.  As a Clinical Pharmacokineticist in Gaithersburg, MD, you’ll play a pivotal role in channeling our scientific capabilities to make a positive impact on changing patients’ lives.

We’re constantly pushing the boundaries of science to deliver life-changing medicines to patients, with a passion for discovery and a pipeline to show for it. We’re pioneering innovative research and exploring novel pathways across key therapeutic areas including oncology, respiratory, inflammation and autoimmunity, cardiovascular and metabolic disease, and infection and vaccines. And we’re industry-leading in immunology, protein engineering and translational science. We offer a unique and strong collaborative network as part of the AstraZeneca family, as together we explore synergies between small and large molecules.

MedImmune has a dynamic environment that fosters collaboration and innovation. We attract top minds, and we nurture and build top talent.

Main Duties and Responsibilities

In this role, you will function as the Global Clinical Pharmacology, Pharmacometrics and DMPK (CPD) project leader and team representative for biotherapeutic products at various stages of research and development. You will be responsible for all aspects of PK/PD-related support for biotherapeutic products, including design of studies, analysis and reporting of data, and communication of data in regulatory documents and meetings and are expected to function with minimal supervision

You will have the opportunity to represent the global group on cross-functional project teams involved in the discovery, nonclinical and clinical development of biotherapeutics;  plan, design and analyze pharmacokinetic, pharmacodynamics and efficacy data from preclinical and clinical studies; and collaborate with toxicologists ,biostatisticians, regulatory specialists, clinicians and clinical operation managers on the design, monitoring, and reporting of nonclinical safety studies.  You’ll conduct translational PK/PD modeling and simulation to support dose selection, designs of PK/PD and safety assessment studies, and dosing justifications for preclinical and clinical studies.


Essential Requirements

  • PhD or Pharm D degree in pharmacokinetics, pharmaceutics, pharmacology, or a related field in the biological sciences             
  • 2-3 years of PK/PD modeling experience in industry, government or academic institutions
  • Good understanding of pharmacokinetic and pharmacodynamic principles
  • Proficiency with various modeling software (i.e. NONMEM, R, S+, etc.) and standard noncompartmental data analysis software (Phoenix/WinNonlin) is required
  • Expertise in other modeling software (e.g., MATLAB, Berkeley Madonna, etc.) is highly desirable
  • Knowledge of bioanalytical expertise, especially of biologics is desirable
  • Experience in PKPD modeling and simulation
  • Good communication skills and ability to work in a cross-functional team environment

Next Steps – Apply today!

To be considered for this exciting opportunity, please complete the full application on our website at your earliest convenience – it is the only way that our Recruiter and Hiring Manager can know that you feel well qualified for this opportunity.  If you know someone who would be a great fit, please share this posting with them.

AstraZeneca is an equal opportunity employer. AstraZeneca will consider all qualified applicants for employment without discrimination on grounds of disability, sex or sexual orientation, pregnancy or maternity leave status, race or national or ethnic origin, age, religion or belief, gender identity or re-assignment, marital or civil partnership status, protected veteran status (if applicable) or any other characteristic protected by law.