Bioinformatics Analyst (NCI) - Frederick, MD | Biospace
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Bioinformatics Analyst (NCI)

Leidos Biomedical Research, Inc.

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Location:
Frederick, MD
Posted Date:
6/9/2017
Position Type:
Full time
Job Code:
637673
Salary:
Required Education:
Bachelors Degree
Areas of Expertise Desired:

Job Description

PROGRAM DESCRIPTION
The Molecular Characterization Laboratory (MoCha) is part of Leidos Biomedical Research’s Clinical Research Directorate (CRD) at the Frederick National Laboratory for Cancer Research. The MoCha Laboratory is responsible for providing high-level research in support of the NCI-Cancer Diagnostics Program (CDP) within the Division of Cancer Treatment and Diagnosis (DCTD). MoCha is charged with the development and application of genomic assays for use in medical research and diagnostics for DCTD-sponsored national extramural clinical trials.

JOB DESCRIPTION
Provide substantial bioinformatics support for the MoCha clinical laboratory, including the analysis and interpretation of high throughput genomic data
Provide expertise in the biological interpretation of results, including mutation impact assessment, expression analysis, statistics support and prioritization of identified loci/genes lists, classification model building and determining correlation with clinical data derived from patients
Interact with investigators throughout the entire experimental process from study design to result interpretation including manuscript preparation
Provide support to lab staff in the application of basic data analysis and study design
Provide bioinformatics knowledge as a shared team resource
Maintain and track complex data for multiple projects
Work with lab managers to update genetic information in databases
Work closely with clinical lab staff to provide computation resources and to support data analysis and storage
Coordinate and integrate software applications and databases within the larger group including the Bethesda, Frederick, and Shady Grove NCI campuses
This position is located in Frederick, MD.

Requirements

BASIC QUALIFICATIONS
To be considered for this position, you must minimally meet the knowledge, skills, and abilities listed below:

This is a dual level requisition. It may be filled at either a Bioinformatics Analyst II or Bioinformatics Analyst III level.

Basic Qualifications for a Bioinformatics Analyst II:
Possession of a Bachelor's degree from an accredited college/university according to the Council for Higher Education Accreditation (CHEA) in a field related to biomedical science/bioinformatics/math/statistics/computer
Foreign degrees must be evaluated for U.S. equivalency
A minimum of two (2) years related computational experience in a biological/medical research laboratory environment with a strong background in bioinformatics application development
Basic Qualifications for a Bioinformatics Analyst III:
Possession of a Bachelor's degree from an accredited college/university according to the Council for Higher Education Accreditation (CHEA) in a field related to biomedical science/bioinformatics/math/statistics/computer
Foreign degrees must be evaluated for U.S. equivalency
A minimum of five (5) years related computational experience in a biological/medical research laboratory environment with a strong background in bioinformatics application development
Both the Bioinformatics Analyst II and III positions require:
Experience in next generation sequence analysis (NGS) including quality metrics, mapping, variant calling and biological interpretation, and experience with analysis of large genomic data sets including integration with data available from public or private sources.
Hands-on experience in data processing and analyzing sequencing, expression and other array data including quality and biological assessment are also essential.
Proficiency in Unix (Linux) system, scripting and programming languages such as Shell, R, Python, JavaScript, Perl, Java, SQL and bioinformatics tools and database management.
Statistical analysis of complex biological data
Experience and demonstrated success in a team-oriented environment and excellent communication skills (written and oral)
Strong organizational skills and information tracking experience for data with complex structure
Ability to identify and solve complex problems
Must be able to obtain and maintain a Security Clearance

PREFERRED QUALIFICATIONS
Candidates with these desired skills will be given preferential consideration:
Peer reviewed publications demonstrating knowledge of the biology of cancer
Experience with Ion Torrent systems, including the Ion Reporter system
Experience in data integration, database construction, application development and visualization
Experience in porting applications to a web environment and working with workflow tools and applications