Leidos Biomedical Research, Inc. (LBRI), a wholly owned subsidiary of Leidos, operates the Frederick National Laboratory for Cancer Research (FNLCR). FNLCR is a Federally Funded Research and Development Center (FFRDC) sponsored by the National Cancer Institute (NCI). It is the only FFRDC dedicated to biomedical research. Through its status as an FFRDC, FNLCR provides NCI and others with a unique national resource to accelerate the development and delivery of effective preventive, diagnostic, and therapeutic products for cancer and AIDS.
The breadth of FNLCR’s activities spans the research and development spectrum, including investigator-initiated, hypothesis-driven research into cancer and AIDS; advanced technology programs focused on genetics and genomics, proteins and proteomics, imaging, nanotechnology, bioinformatics, and laboratory animal sciences; clinical operations in support of NCI and National Institute of Allergy and Infectious Diseases (NIAID)-sponsored clinical trials, as well as NCI drug discovery and development efforts; and management and operations of biopharmaceutical development and manufacturing programs under current Good Manufacturing Practice conditions for NCI and NIAID. Administrative, procurement, financial, safety, and facilities support is provided to these R&D activities through state-of-the-art business processes. LBRI has approximately 1,900 employees and manages an annual operating budget of approximately $450M.
For more information about Leidos Biomedical Research Inc., please visit our webpage at https://www.leidos.com/about/companies/leidos-biomedical-research.
The Advanced Biomedical Computing Center (ABCC) is a part of the Data Science and Information Technology Program at Leidos Biomedical Research, Inc. The ABCC provides technology development, scientific consultation, collaboration and training, and high-performance computing support to the NCI and NIH scientists and staff.
This position description does not represent a current opening but may be used to identify candidates with skills and experience for positions within Leidos Biomedical Research that frequently become available. Candidates who express an interest may be considered for future positions at Leidos Biomedical Research.
The ABCC is seeking Bioinformatics Analyst candidates at all levels to work in the NCI Center for Cancer Research (CCR) Collaborative Research Resource (CCBR). The CCBR provides collaborative bioinformatics support to CCR investigators at the National Cancer Institute (NCI). CCBR bioinformatics analysts are responsible for
• The analysis and interpretation of high-throughput biomedical data generated by microarray, next-generation sequencing, proteomics and metabolomics platforms
• Designing, developing and deploying robust workflows, as well as custom scripts, to support the analysis of high-throughput data
• Mining proprietary and publicly available biological data to generate novel hypotheses or insights
• Presenting analysis results, in a clear and concise manner, to scientific audiences. Bioinformatics Analysts are expected to work effectively as a member of a team; coordinate activities among other groups located at the Bethesda, Frederick, Rockville and Gaithersburg NCI campuses; follow sound scientific practices and maintain effective documentation of activities and analyses. Majority of time will be spent on the main NIH campus in Bethesda.
• Bachelor’s, Masters or PhD degree in life science/bioinformatics/math/physics/computer related field from an accredited college according to the Council for Higher Education Accreditation (CHEA)
• Foreign degrees must be evaluated for U.S. Equivalency.
Below are the typical skills we are looking for in candidates:
• Processing high throughput biomedical data: data cleaning, normalization, analysis, interpretation and visualization
• Data analysis for complex experiments
• Experience with high throughput analysis pipelines such as, metagenomics, ChIPSeq, RNASeq, ExomeSeq, microarray analysis
• Experience in using tools for NGS data-processing tools
• Familiarity with public databases: NCBI, Ensembl, TCGA, cBioPortal, Broad FireHose
• Knowledge of database programming and working in a cluster environment
• Ability to work in collaborative environment and contribute to team projects
• Ability to work without close supervision
Below are the desired skills we are looking for in candidates:
• Applied statistics and design of experiments
• Application development experience
• Experience in submitting data sets to public repositories
• Management of large genomic data sets including integration with data available from public sources
• Knowledge of cancer biology
• Experience with bioinformatics tools such as: Novoalign, STAR, BWA, GATK, Samtools, Annotator, SnpEff, Limma, EdgeR, DESeq2
• Proficiency in one, preferably two, of the following programming languages: Perl, Python, R, Java and C/C++
This position description does not represent a current opening but may be used to identify candidates with skills and experience for positions within Leidos Biomedical Research that frequently become available. Candidates who express an interest may be considered for future positions at Leidos Biomedical Research
Leidos is a global science and technology solutions leader working to solve the world’s toughest challenges in the defense, intelligence, homeland security, civil, and health markets. The company’s 33,000 employees support vital missions for government and commercial customers. Headquartered in Reston, Virginia, Leidos reported pro forma annual revenues of approximately $10 billion for the fiscal year ended January 1, 2016 after giving effect to the recently completed combination of Leidos with Lockheed Martin's Information Systems & Global Solutions business (IS&GS). For more information, visit www.Leidos.com. The company’s diverse employees support vital missions for government and commercial customers. Qualified women, minorities, individuals with disabilities and protected veterans are encouraged to apply. Leidos is an Equal Opportunity Employer.