Bioanalytical Scientist - La Jolla, CA | Biospace
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Bioanalytical Scientist

Synthetic Genomics, Inc.

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Location:
La Jolla, CA
Posted Date:
5/16/2017
Position Type:
Full time
Job Code:
17-0031
Salary:
Required Education:
Doctorate/PhD
Areas of Expertise Desired:

Job Description

At Synthetic Genomics, Inc., we are dedicated to developing and commercializing genomic-driven solutions to address global challenges. We are currently seeking a Bioanalytical Scientist within our Analytical Chemistry group to join our fast-growing, dynamic and collaborative team in La Jolla, CA.

The Bioanalytical Scientist provides technical expertise and hands-on bioanalytical method development within the Analytical Chemistry laboratory in support of all of SGI’s business units’ needs. The successful candidate will have a strong background in protein mass spectrometry and will be abreast of modern protein mass spectrometry tools and techniques. He or She will be responsible for designing and conducting laboratory experiments, interpreting complex datasets, reporting results to supervisors, and for supporting cross-functional collaborations across diverse research programs.

Requirements

Required Skills
•   The Bioanalytical Scientist will develop and implement mass spectrometry based analytical methods for full protein characterization including post-translational modifications. Hands-on experience with characterization of other macromolecules is a strong plus.  
•   Expert knowledge in sample preparation for protein mass spec, mass spectrometer maintenance/operation and data analysis is required.
•   A strong background in mass spectrometry including top down and bottom-up proteomics and hands-on proficiency with instruments such as Thermo Q Exactive Plus, Thermo LTQ Orbitrap XL and Agilent 6538 QTof is required.
•   A detailed working knowledge of analytical software packages from both Agilent and Thermo is required
•   A detailed understanding of liquid chromatography method development is required and troubleshooting/experience with other analytical techniques such as GC/MS and spectrophotometric/electrophoretic techniques is desirable.
•   A working knowledge of biophysical characterization methods is a strong plus.
•   The candidate should have a track record of successful independent research and also be able to work efficiently and collaboratively in a fast-paced team environment.
•   Strong organizational skills, orientation to detail, ability to multitask and prioritize effectively are required.
•   Critical thinking skills, a high degree of self-motivation, flexibility and adaptability to changing priorities and resources are necessary.
•   The candidate must possess excellent interpersonal skills, have strong oral and written communication abilities and will be expected to contribute significantly to the overall success of scientific program(s), on-going projects, critical patents, grants and scientific publications.

Required Experience
•   A Ph.D. in Analytical Chemistry, Biochemistry, Physical Chemistry, or other relevant discipline with 0-5years hands-on post-degree experience in protein based mass spectrometry in an academic or industrial setting
•   Demonstrated state-of-the-art technical capabilities, particularly with protein mass spectrometry
•   A strong, diverse knowledge of protein chemistry, biochemistry, organic chemistry, inorganic chemistry and synthetic biology
•   Experience with handling and analysis of complex biological samples
•   Experience with modern mass spectrometry based data acquisition and analysis software
•   Proven ability to operate, maintain, and troubleshoot versatile analytical instrumentation to maintain high standards of performance
•   Experience working with external contractors, such as partner companies or external laboratories involved in chemical analysis