Associate Scientist II/Scientist I-Protein - (Gaithersburg, MD) - Gaithersburg, MD | Biospace
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Associate Scientist II/Scientist I-Protein - (Gaithersburg, MD)

MedImmune, LLC

Gaithersburg, MD
Posted Date:
Position Type:
Full time
Job Code:
Required Education:
Masters Degree
Areas of Expertise Desired:

Job Description

                                       Location:Gaithersburg, United States
Job reference: R-001657

Posted date: Dec. 01, 2016


   If you’re inspired by the possibilities of science to change lives and you thrive when making brave decisions – join us.  

   MedImmune is the worldwide biologics research and development arm of AstraZeneca. Here, you’ll have the opportunity to make a difference in people’s lives every day. As one of the world’s premier biotechnology companies, our mission is centered on delivering life-changing products that advance world health, and help fight and cure disease.  As an Associate Scientist II/Scientist I in Gaithersburg, MD, you’ll play a pivotal role in channeling our scientific capabilities to make a positive impact on changing patients’ lives.  


   We’re constantly pushing the boundaries of science to deliver life-changing medicines to patients, with a passion for discovery and a pipeline to show for it. We’re pioneering innovative research and exploring novel pathways across key therapeutic areas including oncology, respiratory, inflammation and autoimmunity, cardiovascular and metabolic disease, and infection and vaccines. And we’re industry-leading in immunology, protein engineering and translational science. We offer a unique and strong collaborative network as part of the AstraZeneca family, as together we explore synergies between small and large molecules.  


   MedImmune has a dynamic environment that fosters collaboration and innovation. We attract top minds, and we nurture and build top talent.  

   Main Duties and Responsibilities  



  •      The successful candidate will work in the Late Stage Characterization Group within the Analytical Sciences Department.    
  •      Candidate will carry out detailed characterization of biopharmaceutical products, such as humanized monoclonal antibodies, antibody-drug conjugates, and recombinant proteins.    
  •      Candidate will write characterization reports, quality attribute summary reports, draft BLA and prepare regulatory responses.    
  •      Candidate will also be responsible for product variant isolation / enrichment and characterization, identification of protein degradation pathways, structure-functional analysis, and determination of critical quality attributes.    
  •      Candidate will work on complex and technically demanding projects where analysis of data requires an evaluation of multiple variables.    
  •      Candidate will make detailed experimental observations, review and analyze data, interpret experimental results, and summarize for presentations and reports.    
  •      Candidate will present scientific data to both internal audiences within the company and external scientific colleagues.    
  •      Candidate will follow SOPs, policies, and regulations, and to perform routine lab equipment maintenance is required.    
  •      Position will require constant collaborative interactions with co-workers across functional groups, he/she must be able to work in a matrix structure and interface with different groups within research and development.    


   Essential Requirements  



  •      BS, MS, Ph.D. in Chemistry or Biochemistry    


  •      BS degree with 6-10 years of relevant experience    
  •      MS degree with 3-6 years of relevant experience    
  •      PhD degree with 0-3 years relevant experience      


  •      Protein chemistry, including structural characterization using a variety of analytical techniques.    
  •      Analytical techniques such as such as HPLC, gel electrophoresis, cIEF, and mass spectrometry.    
  •      Knowledge on protein function and bioassay is preferred.    
  •      Excellent writing skill is essential for this role.    

   Desirable Requirements  

  •      Great teamwork and communication skills, both verbal and written, are critical.    
  •      Good multi-tasking, time management and organizational skills are required.    
  •      Time/project management and regulatory filing experience is desirable.    

   Interpersonal Communication  

  •      Excellent writing, verbal and listening skills.  Presentations/reports to senior management and high-level industry audiences.    

   Next Steps – Apply today!  


   To be considered for this exciting opportunity, please complete the full application on our website at your earliest convenience – it is the only way that our Recruiter and Hiring Manager can know that you feel well qualified for this opportunity.  If you know someone who would be a great fit, please share this posting with them.  


   AstraZeneca is an equal opportunity employer. AstraZeneca will consider all qualified applicants for employment without discrimination on grounds of disability, sex or sexual orientation, pregnancy or maternity leave status, race or national or ethnic origin, age, religion or belief, gender identity or re-assignment, marital or civil partnership status, protected veteran status (if applicable) or any other characteristic protected by law.