Associate Scientist I/II - (Gaithersburg, MD) - Gaithersburg, MD | Biospace
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Associate Scientist I/II - (Gaithersburg, MD)

MedImmune, LLC

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Location:
Gaithersburg, MD
Posted Date:
7/20/2017
Position Type:
Full time
Job Code:
R-009461
Salary:
Required Education:
Masters Degree
Areas of Expertise Desired:

Job Description

                             
                                       Location:Gaithersburg, Maryland, United States
Job reference: R-009461

Posted date: Jun. 23, 2017

                                                     
                           


 

   MedImmune is the worldwide biologics research and development arm of AstraZeneca. Here, you’ll have the opportunity to make a difference in people’s lives every day. As one of the world’s premier biotechnology companies, our mission is centered on delivering life-changing products that advance world health, and help fight and cure disease.  As an Associate Scientist I/II, in Gaithersburg, Maryland, you’ll play a pivotal role in channeling our scientific capabilities to make a positive impact on changing patients’ lives.  

   We’re constantly pushing the boundaries of science to deliver life-changing medicines to patients, with a passion for discovery and a pipeline to show for it. We’re pioneering innovative research and exploring novel pathways across key therapeutic areas including oncology, respiratory, inflammation and autoimmunity, cardiovascular and metabolic disease, and infection and vaccines. And we’re industry-leading in immunology, protein engineering and translational science. We offer a unique and strong collaborative network as part of the AstraZeneca family, as together we explore synergies between small and large molecules.  

   MedImmune has a dynamic environment that fosters collaboration and innovation. We attract top minds, and we nurture and build top talent.  

   Major Duties and Responsibilities    

   As the Associate Scientist I/II you will be working in the Antibody Discovery and Protein Engineering department within the Research organization to conduct pre-clinical research and technology development in the area of antibody drug conjugates and bispecific antibodies. You will be responsible for molecular cloning, recombinant protein expression, conjugation of small molecule compound to antibodies using a variety of conjugation modalities, stability assessment, analytical and functional characterization of bispecific antibodies and antibody drug conjugates. Also, you will need to collaborate with biologists, toxicologists; pharmacologists and process scientists to ensure the delivery of bispecific molecules and antibody drug conjugates meet desired biological, biophysical and manufacturability properties.  

Requirements

   Essential Requirements  

       
  •      BS, MS in Molecular Biology, Biochemistry, or related field.    
  •    
  •      A minimum of two years (Associate Scientist I) or five years (Associate Scientist II) of experience in the bio-pharmaceutical industry.    
  •    
  •      A recently obtained PhD (i.e. less than one year) in antibody engineering or related disciplines.    
  •    
  •      Hands on laboratory experience in molecular biology, protein chemistry, antibody or protein engineering, antibody drug conjugates.    
  •  

   Desired Requirements  

       
  •      Proven knowledge with cloning and various analytical methodologies such as affinity purification; size-exclusion chromatography; reverse phase chromatography; hydrophobic interaction chromatography; spectroscopy; mass spectrometry), binding studies (i.e. ELISA, FACS, BIAcore).    
  •    
  •      Hands-on working experience with liquid chromatography mass spectrometry as applied to the characterization of antibody drug conjugates.    
  •    
  •      Ability to provide critical interpretation of results.    
  •    
  •      Ability to multitask and handle multiple priorities in a fast-paced environment.    
  •    
  •      Excellent written and verbal communications skills.    
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  •      Ability to work in cross-functional teams. Great teamwork and communication skills, both verbal and written, are critical.    
  •    
  •      Documented experience with working with bispecific antibodies and / or antibody drug conjugates.    
  •  

   Next Steps – Apply today!  

 

   To be considered for this exciting opportunity, please complete the full application on our website at your earliest convenience – it is the only way that our Recruiter and Hiring Manager can know that you feel well qualified for this opportunity.  If you know someone who would be a great fit, please share this posting with them.  

   AstraZeneca is an equal opportunity employer. AstraZeneca will consider all qualified applicants for employment without discrimination on grounds of disability, sex or sexual orientation, pregnancy or maternity leave status, race or national or ethnic origin, age, religion or belief, gender identity or re-assignment, marital or civil partnership status, protected veteran status (if applicable) or any other characteristic protected by law. AstraZeneca only employs individuals with the right to work in the country/ies where the role is advertised.  

   ~bsp  

 

   *LI-MEDI