Associate Scientist, Downstream Process Development - Summit, NJ | Biospace
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Associate Scientist, Downstream Process Development


Summit, NJ
Posted Date:
Position Type:
Full time
Job Code:
Required Education:
Bachelors Degree
Areas of Expertise Desired:

Job Description


Celgene is a global biopharmaceutical company leading the way in medical innovation to help patients live longer, better lives. Our purpose as a company is to discover and develop therapies that will change the course of human health.  We value our passion for patients, quest for innovation, spirit of independence and love of challenge. With a presence in more than 70 countries - and growing - we look for talented people to grow our business, advance our science and contribute to our unique culture.

This Associate Scientist will work in biologics purification process development group. Reporting to the head of the Downstream Process Development. The successful candidate should have strong technical knowledge, initiative and scientific commitment, and be able to make scientific and technical contributions to downstream process development. He or she should have the ability to work with internal and external partners, and the ability to communicate and connect with all levels of the organization.

Responsibilities will include, but are not limited to, the following:

1.Execute harvest and downstream processing of biologics produced in mammalian cell culture or microbial cell culture.

2.Develop protein purification process.

3.Set up analytical assays for in process sample testing.

4.Interact with cell line, upstream and analytical development functional groups for the purification of the target molecules to support discovery and preclinical development activities.

5.Perform routine lab activities including buffer preparation, column packing and sample preparations.

6.Design studies to be executed, with supervisor's input.

7.Expand the technical capabilities of the Process Development group, by keeping abreast with new development and introducing new technologies

8.Effectively communicate results through scientific meetings, presentations, discussions and documentation with some inputs from supervisor.

9.Deploy knowledge and technical skills to execute studies in a timely manner.

10.Assist in moving projects forward to manufacture material for pre-clinical development and support manufacturing for clinical supplies.




Skills/Knowledge Required:

?Experience with downstream process development including chromatography,    filtration, AKTA FPLC systems (particularly unicorn software).

?Knowledge of analytical techniques including HPLC/UPLC, spectrophotometry,   SDS-PAGE, Western-blot, protein assays, and bioactivity assays.

?Experience in instrument maintenance, trouble-shooting and data                        interpretation.

?Able to work independently with minimum supervision

?Demonstrated ability to function in a collaborative team oriented environment.

?Good verbal and written communication skills.

Celgene is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status.

Celgene complies with all applicable national, state and local laws governing nondiscrimination in employment as well as employment eligibility verification requirements of the Immigration and Nationality Act. All applicants must have authorization to work for Celgene in the U.S.