Research Associate - San Diego, CA | Biospace
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Research Associate

R&D Partners

Location:
San Diego, CA
Posted Date:
4/6/2017
Position Type:
Consultant
Job Code:
Salary:
Required Education:
Bachelors Degree
Areas of Expertise Desired:
Antibody, Elisa,

Job Description

Primarily be responsible for developing and performing binding assays, kinetic profiling assays, competition assays, efficacy assays and epitope binning of early therapeutic candidates using a wide range of biophysical and biochemical methods including Biacore, MASS-1, Octet, FRET, ELISA, etc. 
Implement and validate protocols. 
Reviewing literature for technical support. 
Data analysis. 
With assistance, executes experiments, conducts analysis and reports results. 
Work with minimal direction to complete assigned tasks. 

Requirements

At least 2 years of industry experience in bioanalytical and biophysical characterization of monoclonal antibodies, Fc-fusion proteins, peptides and antibody-drug conjugates (ADCs). 
***MUST have experience with Bicaore or SPR instruments.*** 
Proven track record of developing binding assays for monoclonal antibodies and other forms of biologics candidates using all or any of the following techniques: Biacore, MASS-1, Octet, HTRF, AlphaScreen, ELISA. 
Thermal stability determination using DSC, DSF and formulation screen to identify ideal storage buffer condition. 
Experience in SDS PAGE is a plus. 
Antibody conjugation experience is a plus. 
Experience in protein expression and purification is a plus. 
Mass spectrometry: Intact mass determination of antibodies and Fc-fusion protein can be an added advantage. 

Bachelor’s or Master’s degree in Biochemistry or related discipline with 2 years of hands on experience in industry focusing on Biologics. NO PHDs.

Candidates local to San Diego