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Associate Scientist - Cardiovascular and Metabolic Disease

Pfizer Inc.

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Location:
Cambridge, MA
Posted Date:
7/25/2014
Position Type:
Full time
Job Code:
94901.60383
Salary:
Required Education:
Bachelors Degree
Areas of Expertise Desired:

Job Description

Org Marketing Statement
All over the world, Pfizer colleagues are working together to positively impact health for everyone, everywhere. Each position at Pfizer touches and contributes to the success of our business and our world. That's why, as one of the global leaders in the biopharmaceutical industry, Pfizer is committed to seeking out inspired new talent who share our core values and mission of making the world a healthier place.

Responsibilities
The Cardiovascular and Metabolic Diseases Research Unit is focused on identifying targets and developing compounds for the treatment of Diabetes and its complications. We are seeking motivated self-aware individuals with excellent oral and written communication skills and a deep interest in biological sciences. The successful candidate will able to learn quickly, ask questions as needed, function in a team environment and have some knowledge of the drug development process.

Activities will include:
*Mammalian cell culture and transfection/transduction, RNAi mediated gene silencing
nucleic acid/protein isolation and quantitation, protein extraction and purification, PCR, RT-PCR, Westerns, ELISAs, immunoprecipitation, and tissue extractions.
*Assay development execution in support of identifying and optimizing drug candidates.
Animal dosing and handling (rats and/or mice) with measures of metabolic endpoints. Characterization of responses off islet beta cells to endocrine, developmental, pharmacological and metabolic perturbations.
*Quantification and translation of experimental results to advance understanding of how
metabolic pathways and complex physiological systems are altered by the diabetic- disease state, and how they respond/adapt to therapeutic interventions
*Maintenance of laboratory notebook records and adherence to safety policies is strictly required.

Qualifications
Education and Experience:
-BA, BS or MS with laboratory experience in appropriate scientific areas relevant to this position

A degree in the following is strongly preferred:
*Biochemistry, Cell Biology, Physiology, Biomedical Engineering, Chemical Biology,
Quantitative Biology

A concentration in one of the following quantitative studies is strongly preferred:
*Chemical Engineering, Applied Mathematics, Computational Biology, Physics, or
another area applying math, statistics, and/or computer science to biology

Technical Skills Requirements:
Successful candidates will have 0-3 years post-graduate research experience and demonstrated skills in the following:
*Effective experimentalist, proficient in a range of lab techniques detailed above, and
experience in analytical and/or bioanalytical methods, with the capability of applying this in an efficient, highly interactive, goal-oriented team environment.
*Ability to grasp complex procedures, and adapt appropriately.
*Proven verbal and written communication skills, and the ability to work in a
collaborative team environment.
*A working knowledge of statistics as it applies to experimental design and be able to
conduct data analysis using Microsoft Excel, GraphPad Prism or equivalent software.
*A strong technical background in mathematics and/or engineering, including an
understanding of the use quantitative models for understanding complex systems.
*Ability to complete experiments and present results in individual and group settings,
including experience using Microsoft PowerPoint or equivalent software for this purpose.

Equal Employment Opportunity
Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.

Requirements

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