Sr. Scientist/Scientist - Preclinical Bio-Imaging, Agensys - Santa Monica, CA

Astellas Pharma US, Inc.

Location: Santa Monica, California 00000
Posted on: 5/5/2009 11:40:36 AM
Postion type: Full time
Job Code: 354783
Required Education:
Salary:

DESCRIPTION
At Agensys, we're changing tomorrow by moving oncology forward. We’ve developed a pipeline of novel therapeutic fully human monoclonal antibodies (MAbs) to treat solid tumors based on our own proprietary targets. We have discovered and validated a portfolio of clinically relevant targets in 14 different cancer types. Our pipeline includes therapeutic MAbs to multiple cancer indications that are at different stages of clinical and pre-clinical development. Our parent company, Astellas Pharma US helps us shine. Together we are the bright spot in the pharmaceutical industry – not just because of what we do, but in the way we do it. If you are looking for a company where you can change a life, make a dream come true, and light the way for a better tomorrow, this is the place for you. Sr. Scientist/Scientist- Preclinical Bio-Imaging We are seeking a hands-on scientist to direct internal efforts aimed at developing preclinical Bio-Imaging capabilities at Agensys. The qualified candidate will establish, manage and maintain Agensys new Bio-Imaging facility. He/she will design, execute, and interpret in vivo studies with antibody therapeutics that employ imaging modalities including micro PET/CT in a preclinical, translational setting. The qualified candidate will establish protocols for using bioimaging instruments and be responsible for managing the equipment and training and supervising users engaged in radiopharmaceutical research. The successful applicant will be expected to provide research leadership, technical expertise, and mentorship in the broad area of bio-imaging. The successful candidate will also play an integral role in a cross-disciplinary team of scientists involved in the discovery and evaluation of biomarkers and mechanism of action for emerging antibody therapeutics for oncology. The position offers a unique opportunity for a talented scientist to work in a dynamic and innovative environment and to develop their career at the interface of basic research and drug discovery.

REQUIREMENTS:
• PhD with a background in radiology, cancer or cell biology that includes analyzing and interpreting imaging data• Minimum of 4-5 years of industrial or academic experience in relevant fields• Research experience in small animal imaging, managing relevant equipment and interpreting radiopharmaceutical experiments is critical• Experience with use of in vivo models to explore PK, PD and efficacy and their relationship with biomarker expression is highly desirable • A proven publication record is desirable• Ability to take charge and drive projects to completion• Effective interpersonal and technical communication skills with ability to report and communicate study outcomes to project team(s)• Ability to work in a team oriented environment and oversee portions of studies performed by other groups or departments• Understanding of ALAAC accreditation and IACUC protocols is highly desirable. Label