Research Associate, Ophthalmology

Rinat

Location: South San Francisco, California-San Francisco 94080
Posted on: 6/18/2008 11:37:58 AM
Postion type: Full time
Job Code: 080531
Required Education: Bachelor's Degree
Salary:

DESCRIPTION
Rinat, located in South San Francisco, is part of the Pfizer Biotherapeutics and Bioinnovation Center (BBC). The center works both independently and interdependently with Pfizer Global Research and Development (PGRD), creating and overseeing a federation of units and collaborations with the academic, biomedical, biotech communities, while collaborating closely with PGRD to discover and develop protein therapeutics that address significant unmet medical needs.

Major responsibilities will include experimental design and execution of physiogical and histological experiments with the goal of developing novel therapeutic approaches to fight retinal degenerative diseases.

- Perform physiological analysis of retinal function using ERG, VEP, angiography, etc.
- Perform embedding and sectioning tissue for immunohistochemistry, immunofluorescence, in situ hybridization, sample evaluation by photomicroscopy, with subsequent quantification of results. Experience with ImageJ is plus.
- Perform small rodent surgery. Experience in vitreal and subretinal injections, and in stereotactic techniques is plus.
- Routinely perform dosing, blood draw, ophtalmoscopy.
- Develop formulations and evaluate their efficacy and stability using cell based and in vivo assays.
- Document data in lab notebook and ensure periodic peer review.
- Present data for review, group discussions, and team meetings.
- Multi-task effectively and prioritize multiple projects with guidance.

REQUIREMENTS:
- BS/MSc in physiology or related field with a minimum of 3 years of laboratory experience.
- Strong skills in in vivo physiology, especially in retinal and neurological disease models.
- Experience in establishing murine models of disease is a plus.
- Strong fundamentals in histology, biochemistry, molecular biology.
- Highly motivated with a strong attitude towards learning.
- Must be able to work productively in a fast-paced collaborative team.
- Excellent communication skills are essential.

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as employment eligibility verification requirements of the Immigration and Nationality Act.

All applicants must have authorization to work for Pfizer in the U.S. In certain circumstances it may be advantageous to Pfizer to support the application(s) for temporary visa classification and/or sponsor applications for permanent residence so that a foreign national colleague can accept or remain in a work assignment in the U. S. For certain classes of temporary visas, the resulting work authorization may be specific to Pfizer and the specific job and/or work site. Pfizer may at its business discretion decide to or refrain from obtaining, maintaining and/or extending the temporary visa status and/or sponsoring a colleague for permanent residency and /or employment eligibility, considering factors such as availability of qualified U.S. workers and the colleague's long-term prospects for securing lawful permanent residence, among other reasons. Employment applicants requiring immigration sponsorship must disclose, when initial application for employment is made, whether or not they are legally authorized to work for Pfizer in the U.S. and, if so, whether that authorization permits them to work in the job they seek. In no case should Pfizer's support of a colleague's temporary visa application or sponsorship of a colleague for permanent residence be construed to guarantee success of that application or amend or otherwise invalidate the "at-will" employment relationship between the colleague and Pfizer.
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